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Details
Link-It Detail - Jax Mouse Phenotype - abnormal NK cell differentiation
Debug Stats
  • ### Total Build Time: 21 ms 25.078 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 392 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 443 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 202 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=5 ms Completed: 5 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.017 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 13.614 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 8.112 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.170 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal NK cell differentiation MP:0008053
Definition (1)
atypical production of or inability to produce mature lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Synonyms (1)
"abnormal natural killer cell differentiation" EXACT
Parents (2)
img abnormal NK cell morphology MP:0005068
img abnormal lymphopoiesis MP:0002401
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal NK cell morphology MP:0005068
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal NK cell morphology MP:0005068
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal NK cell morphology MP:0005068
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal lymphopoiesis MP:0002401
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal lymphopoiesis MP:0002401
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal lymphopoiesis MP:0002401
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal lymphopoiesis MP:0002401
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal lymphopoiesis MP:0002401
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal lymphopoiesis MP:0002401
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal lymphopoiesis MP:0002401
Genes (13)

Species:
human : 13
SpeciesGeneGeneIdGene NameEvidence
HumanKLRC4-KLRK1100528032
Click here to display 17 evidence detail records.
HumanS1PR553637sphingosine-1-phosphate receptor 5
Click here to display 17 evidence detail records.
HumanTBX2130009T-box 21
Click here to display 17 evidence detail records.
HumanKLRK122914killer cell lectin-like receptor subfamily K, member 1
Click here to display 17 evidence detail records.
HumanTUSC211334tumor suppressor candidate 2
Click here to display 17 evidence detail records.
HumanSPHK18877sphingosine kinase 1
Click here to display 17 evidence detail records.
HumanPIK3CG5294phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Click here to display 17 evidence detail records.
HumanPIK3CD5293phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Click here to display 17 evidence detail records.
HumanNFIL34783nuclear factor, interleukin 3 regulated
Click here to display 17 evidence detail records.
HumanIL15RA3601interleukin 15 receptor, alpha
Click here to display 17 evidence detail records.
HumanIL11RA3590interleukin 11 receptor, alpha
Click here to display 17 evidence detail records.
HumanGFI12672growth factor independent 1 transcription repressor
Click here to display 17 evidence detail records.
HumanS1PR11901sphingosine-1-phosphate receptor 1
Click here to display 17 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008053abnormal NK cell differentiation0self