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Details
Link-It Detail - Jax Mouse Phenotype - decreased NK cell number
Debug Stats
  • ### Total Build Time: 534 ms 34.666 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 376 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 416 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 194 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 1.022 KB
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 572 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 13.669 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=510 ms Completed: 510 ms rowSize= 17.146 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.162 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
decreased NK cell number MP:0008045
Definition (1)
reduction in the number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Synonyms (1)
"decreased natural killer cell number" EXACT
Parents (2)
img decreased lymphocyte cell number MP:0005016
img abnormal NK cell number MP:0008043
Children (1)
img absent NK cells MP:0008046
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img decreased lymphocyte cell number MP:0005016
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img decreased lymphocyte cell number MP:0005016
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img decreased lymphocyte cell number MP:0005016
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img decreased lymphocyte cell number MP:0005016
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img decreased lymphocyte cell number MP:0005016
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal NK cell number MP:0008043
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal NK cell number MP:0008043
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal NK cell number MP:0008043
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal NK cell number MP:0008043
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal NK cell number MP:0008043
Genes (55)

Species:
human : 55
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SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
Click here to display 103 evidence detail records.
HumanIFNE338376interferon, epsilon
Click here to display 103 evidence detail records.
HumanCARD1184433caspase recruitment domain family, member 11
Click here to display 103 evidence detail records.
HumanNIPAL357185NIPA-like domain containing 3
Click here to display 103 evidence detail records.
HumanKMT2E55904lysine (K)-specific methyltransferase 2E
Click here to display 103 evidence detail records.
HumanS1PR553637sphingosine-1-phosphate receptor 5
Click here to display 103 evidence detail records.
HumanNLK51701nemo-like kinase
Click here to display 103 evidence detail records.
HumanTBX2130009T-box 21
Click here to display 103 evidence detail records.
HumanPYCARD29108PYD and CARD domain containing
Click here to display 103 evidence detail records.
HumanDKK327122dickkopf WNT signaling pathway inhibitor 3
Click here to display 103 evidence detail records.
HumanZBTB122890zinc finger and BTB domain containing 1
Click here to display 103 evidence detail records.
HumanTUSC211334tumor suppressor candidate 2
Click here to display 103 evidence detail records.
HumanTXNIP10628thioredoxin interacting protein
Click here to display 103 evidence detail records.
HumanNPC210577Niemann-Pick disease, type C2
Click here to display 103 evidence detail records.
HumanATG710533autophagy related 7
Click here to display 103 evidence detail records.
HumanIKZF110320IKAROS family zinc finger 1 (Ikaros)
INFERRED
HumanEBI310148Epstein-Barr virus induced 3
Click here to display 103 evidence detail records.
HumanTOX9760thymocyte selection-associated high mobility group box
Click here to display 103 evidence detail records.
HumanAIM29447absent in melanoma 2
Click here to display 103 evidence detail records.
HumanNCR19437natural cytotoxicity triggering receptor 1
Click here to display 103 evidence detail records.
HumanSPHK18877sphingosine kinase 1
Click here to display 103 evidence detail records.
HumanIKBKG8517inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Click here to display 103 evidence detail records.
HumanEOMES8320eomesodermin
Click here to display 103 evidence detail records.
HumanCXCR47852chemokine (C-X-C motif) receptor 4
Click here to display 103 evidence detail records.
HumanWAS7454Wiskott-Aldrich syndrome
Click here to display 103 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008045decreased NK cell number0self