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Details
Link-It Detail - Jax Mouse Phenotype - increased NK cell number
Debug Stats
  • ### Total Build Time: 117 ms 28.632 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 376 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 407 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 194 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 1.022 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 13.669 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=91 ms Completed: 91 ms rowSize= 11.672 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.162 KB
  • CONCEPT_ANCILLARY gt=2 ms Completed: 2 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
increased NK cell number MP:0008044
Definition (1)
greater number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Synonyms (1)
"increased natural killer cell number" EXACT
Parents (2)
img increased lymphocyte cell number MP:0005013
img abnormal NK cell number MP:0008043
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img increased lymphocyte cell number MP:0005013
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img increased lymphocyte cell number MP:0005013
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img increased lymphocyte cell number MP:0005013
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img increased lymphocyte cell number MP:0005013
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img increased lymphocyte cell number MP:0005013
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal NK cell number MP:0008043
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal NK cell number MP:0008043
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal NK cell number MP:0008043
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal NK cell number MP:0008043
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal NK cell number MP:0008043
Genes (19)

Species:
human : 19
SpeciesGeneGeneIdGene NameEvidence
HumanBCL11B64919B-cell CLL/lymphoma 11B (zinc finger protein)
Click here to display 41 evidence detail records.
HumanTBX2130009T-box 21
Click here to display 41 evidence detail records.
HumanBCL2L1110018BCL2-like 11 (apoptosis facilitator)
Click here to display 41 evidence detail records.
HumanNCR19437natural cytotoxicity triggering receptor 1
Click here to display 41 evidence detail records.
HumanSPHK18877sphingosine kinase 1
Click here to display 41 evidence detail records.
HumanTNFRSF10A8797tumor necrosis factor receptor superfamily, member 10a
Click here to display 41 evidence detail records.
HumanTNFSF128742tumor necrosis factor (ligand) superfamily, member 12
Click here to display 41 evidence detail records.
HumanCXCR47852chemokine (C-X-C motif) receptor 4
Click here to display 41 evidence detail records.
HumanXPA7507xeroderma pigmentosum, complementation group A
Click here to display 41 evidence detail records.
HumanRAG15896recombination activating gene 1
Click here to display 41 evidence detail records.
HumanPTPRC5788protein tyrosine phosphatase, receptor type, C
Click here to display 41 evidence detail records.
HumanPRKDC5591protein kinase, DNA-activated, catalytic polypeptide
Click here to display 41 evidence detail records.
HumanPRF15551perforin 1 (pore forming protein)
Click here to display 41 evidence detail records.
HumanLCP23937lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
Click here to display 41 evidence detail records.
HumanINPP5D3635inositol polyphosphate-5-phosphatase, 145kDa
Click here to display 41 evidence detail records.
HumanIL183606interleukin 18 (interferon-gamma-inducing factor)
Click here to display 41 evidence detail records.
HumanFOXO32309forkhead box O3
Click here to display 41 evidence detail records.
HumanE2F41874E2F transcription factor 4, p107/p130-binding
Click here to display 41 evidence detail records.
HumanRHOH399ras homolog family member H
Click here to display 41 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008044increased NK cell number0self