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Details
Link-It Detail - Jax Mouse Phenotype - abnormal NK cell number
Debug Stats
  • ### Total Build Time: 65 ms 29.471 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 374 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 416 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 193 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=11 ms Completed: 11 ms rowSize= 1.025 KB
  • CONCEPT_CHILDREN gt=10 ms Completed: 10 ms rowSize= 1.018 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=11 ms Completed: 11 ms rowSize= 10.996 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=29 ms Completed: 29 ms rowSize= 14.166 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal NK cell number MP:0008043
Definition (1)
deviation in the number of lymphocytes that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells
Synonyms (1)
"abnormal natural killer cell number" EXACT
Parents (2)
img abnormal lymphocyte cell number MP:0000717
img abnormal NK cell morphology MP:0005068
Children (2)
img decreased NK cell number MP:0008045
img increased NK cell number MP:0008044
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal lymphocyte cell number MP:0000717
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal lymphocyte cell number MP:0000717
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal lymphocyte cell number MP:0000717
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal lymphocyte cell number MP:0000717
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal lymphocyte cell number MP:0000717
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal NK cell morphology MP:0005068
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal NK cell morphology MP:0005068
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal NK cell morphology MP:0005068
Genes (69)

Species:
human : 69
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
INFERRED
HumanIFNE338376interferon, epsilon
INFERRED
HumanCARD1184433caspase recruitment domain family, member 11
INFERRED
HumanBCL11B64919B-cell CLL/lymphoma 11B (zinc finger protein)
INFERRED
HumanNIPAL357185NIPA-like domain containing 3
INFERRED
HumanKMT2E55904lysine (K)-specific methyltransferase 2E
INFERRED
HumanS1PR553637sphingosine-1-phosphate receptor 5
INFERRED
HumanNLK51701nemo-like kinase
INFERRED
HumanTBX2130009T-box 21
INFERRED
HumanPYCARD29108PYD and CARD domain containing
INFERRED
HumanDKK327122dickkopf WNT signaling pathway inhibitor 3
INFERRED
HumanZBTB122890zinc finger and BTB domain containing 1
INFERRED
HumanTUSC211334tumor suppressor candidate 2
INFERRED
HumanTXNIP10628thioredoxin interacting protein
INFERRED
HumanNPC210577Niemann-Pick disease, type C2
INFERRED
HumanATG710533autophagy related 7
INFERRED
HumanIKZF110320IKAROS family zinc finger 1 (Ikaros)
INFERRED
HumanEBI310148Epstein-Barr virus induced 3
INFERRED
HumanBCL2L1110018BCL2-like 11 (apoptosis facilitator)
INFERRED
HumanTOX9760thymocyte selection-associated high mobility group box
INFERRED
HumanAIM29447absent in melanoma 2
INFERRED
HumanNCR19437natural cytotoxicity triggering receptor 1
INFERRED
HumanSPHK18877sphingosine kinase 1
INFERRED
HumanTNFRSF10A8797tumor necrosis factor receptor superfamily, member 10a
INFERRED
HumanTNFSF128742tumor necrosis factor (ligand) superfamily, member 12
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008043abnormal NK cell number0self