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Details
Link-It Detail - Jax Mouse Phenotype - blastoma
Debug Stats
  • ### Total Build Time: 88 ms 18.119 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 344 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 351 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=11 ms Completed: 11 ms rowSize= 571 bytes
  • CONCEPT_CHILDREN gt=22 ms Completed: 22 ms rowSize= 2.787 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.552 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=42 ms Completed: 42 ms rowSize= 11.253 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
blastoma MP:0008021
Definition (1)
a fast growing and invasive tumor composed chiefly or entirely of immature undifferentiated cells that have embryonic characteristics resembling the primordium of the organ in which the tumor arose
Parents (1)
img malignant tumors MP:0002018
Children (6)
img retinoblastoma MP:0006310
img renal hemangioblastoma MP:0003603
img hepatoblastoma MP:0010054
img neuroblastoma MP:0002039
img medulloblastoma MP:0006283
img increased glioblastoma incidence MP:0010727
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img tumorigenesis MP:00020068img malignant tumors MP:0002018
Genes (20)

Species:
human : 20
SpeciesGeneGeneIdGene NameEvidence
HumanNHEJ179840nonhomologous end-joining factor 1
INFERRED
HumanSUFU51684suppressor of fused homolog (Drosophila)
INFERRED
HumanCXCR610663chemokine (C-X-C motif) receptor 6
INFERRED
HumanHTATIP210553HIV-1 Tat interactive protein 2, 30kDa
INFERRED
HumanXRCC57520X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
INFERRED
HumanXRCC47518X-ray repair complementing defective repair in Chinese hamster cells 4
INFERRED
HumanXRCC27516X-ray repair complementing defective repair in Chinese hamster cells 2
INFERRED
HumanTP537157tumor protein p53
INFERRED
HumanSMARCB16598SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
img Jax MP, Pubmed Id: 19808965, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 16099835, MOUSE PHENOTYPE ID: MGI:1328366
HumanRBL25934retinoblastoma-like 2 (p130)
INFERRED
HumanRBL15933retinoblastoma-like 1 (p107)
INFERRED
HumanRAG15896recombination activating gene 1
INFERRED
HumanPTEN5728phosphatase and tensin homolog
INFERRED
HumanPTCH15727patched 1
INFERRED
HumanPIK3CA5290phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
INFERRED
HumanNF14763neurofibromin 1
INFERRED
HumanLIG43981ligase IV, DNA, ATP-dependent
INFERRED
HumanCDKN2C1031cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
INFERRED
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
INFERRED
HumanBRCA2675breast cancer 2, early onset
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008021blastoma0self