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Details
Link-It Detail - Jax Mouse Phenotype - abnormal cellular replicative senescence
Debug Stats
  • ### Total Build Time: 66 ms 21.267 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 408 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 1.045 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.564 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=41 ms Completed: 41 ms rowSize= 16.063 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.178 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal cellular replicative senescence MP:0008007
Definition (1)
anomaly in the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division
Parents (1)
img abnormal cell physiology MP:0005621
Children (2)
img delayed cellular replicative senescence MP:0008009
img early cellular replicative senescence MP:0008008
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053844img abnormal cell physiology MP:0005621
Genes (59)

Species:
human : 59
Page Size
Current 25
  Page 1 of 3
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMCM9254394minichromosome maintenance complex component 9
INFERRED
HumanRAD9B144715RAD9 homolog B (S. pombe)
INFERRED
HumanSUV420H284787suppressor of variegation 4-20 homolog 2 (Drosophila)
INFERRED
HumanSLX484464SLX4 structure-specific endonuclease subunit
INFERRED
HumanCTC180169CTS telomere maintenance complex component 1
INFERRED
HumanACD65057adrenocortical dysplasia homolog (mouse)
INFERRED
HumanSMURF264750SMAD specific E3 ubiquitin protein ligase 2
INFERRED
HumanCDK5RAP255755CDK5 regulatory subunit associated protein 2
INFERRED
HumanUIMC151720ubiquitin interaction motif containing 1
INFERRED
HumanSIRT651548sirtuin 6
INFERRED
HumanPATZ123598POZ (BTB) and AT hook containing zinc finger 1
INFERRED
HumanDICER123405dicer 1, ribonuclease type III
INFERRED
HumanATMIN23300ATM interactor
INFERRED
HumanSCMH122955sex comb on midleg homolog 1 (Drosophila)
INFERRED
HumanSIRT222933sirtuin 2
INFERRED
HumanMTF222823metal response element binding transcription factor 2
INFERRED
HumanZNF27711179zinc finger protein 277
INFERRED
HumanPPP1R13L10848protein phosphatase 1, regulatory subunit 13 like
INFERRED
HumanCUL79820cullin 7
INFERRED
HumanBUB39184BUB3 mitotic checkpoint protein
img Jax MP, Pubmed Id: 16476774, MOUSE PHENOTYPE ID: MGI:1343463
img Jax MP, Pubmed Id: 15208629
img Jax MP, Pubmed Id: 16476774
HumanTP638626tumor protein p63
INFERRED
HumanCDC14B8555cell division cycle 14B
INFERRED
HumanMAPKAPK58550mitogen-activated protein kinase-activated protein kinase 5
INFERRED
HumanUSP47375ubiquitin specific peptidase 4 (proto-oncogene)
INFERRED
HumanUBC7316ubiquitin C
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008007abnormal cellular replicative senescence0self