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Details
Link-It Detail - Jax Mouse Phenotype - decreased retinal ganglion cell number
Debug Stats
  • ### Total Build Time: 46 ms 28.149 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 404 bytes
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  • CONCEPT_GENES gt=40 ms Completed: 40 ms rowSize= 17.132 KB
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Jax Mouse Phenotype (1)
decreased retinal ganglion cell number MP:0006309
Definition (1)
reduced number of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain
Synonyms (1)
"reduced retinal ganglion cell number" EXACT
Parents (2)
img decreased sensory neuron number MP:0000966
img abnormal retinal ganglion cell morphology MP:0008056
Children (1)
img absent retinal ganglion cell MP:0008068
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036318img decreased sensory neuron number MP:0000966
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036317img decreased sensory neuron number MP:0000966
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036317img abnormal retinal ganglion cell morphology MP:0008056
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036318img abnormal retinal ganglion cell morphology MP:0008056
img mammalian phenotype MP:0000001img vision/eye phenotype MP:000539111img abnormal retinal ganglion cell morphology MP:0008056
Genes (26)

Species:
human : 26
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanBARHL2343472BarH-like homeobox 2
Click here to display 47 evidence detail records.
HumanATOH7220202atonal homolog 7 (Drosophila)
Click here to display 47 evidence detail records.
HumanOPA380207optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
Click here to display 47 evidence detail records.
HumanSMOC164093SPARC related modular calcium binding 1
Click here to display 47 evidence detail records.
HumanNEUROD458158neuronal differentiation 4
Click here to display 47 evidence detail records.
HumanPOMGNT155624protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
Click here to display 47 evidence detail records.
HumanTRIM223321tripartite motif containing 2
Click here to display 47 evidence detail records.
HumanBCAR38412breast cancer anti-estrogen resistance 3
Click here to display 47 evidence detail records.
HumanEOMES8320eomesodermin
Click here to display 47 evidence detail records.
HumanMAP3K127786mitogen-activated protein kinase kinase kinase 12
Click here to display 47 evidence detail records.
HumanSOD16647superoxide dismutase 1, soluble
Click here to display 47 evidence detail records.
HumanSLC1A36507solute carrier family 1 (glial high affinity glutamate transporter), member 3
Click here to display 47 evidence detail records.
HumanSLC1A16505solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
Click here to display 47 evidence detail records.
HumanRPL246152ribosomal protein L24
Click here to display 47 evidence detail records.
HumanRBL25934retinoblastoma-like 2 (p130)
INFERRED
HumanRBL15933retinoblastoma-like 1 (p107)
Click here to display 47 evidence detail records.
HumanPOU4F35459POU class 4 homeobox 3
Click here to display 47 evidence detail records.
HumanPOU4F25458POU class 4 homeobox 2
Click here to display 47 evidence detail records.
HumanSERPINF15176serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Click here to display 47 evidence detail records.
HumanPAX25076paired box 2
Click here to display 47 evidence detail records.
HumanOPA14976optic atrophy 1 (autosomal dominant)
Click here to display 47 evidence detail records.
HumanNTRK24915neurotrophic tyrosine kinase, receptor, type 2
Click here to display 47 evidence detail records.
HumanNEUROD14760neuronal differentiation 1
Click here to display 47 evidence detail records.
HumanISL13670ISL LIM homeobox 1
Click here to display 47 evidence detail records.
HumanE2F11869E2F transcription factor 1
Click here to display 47 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0006309decreased retinal ganglion cell number0self