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Details
Link-It Detail - Jax Mouse Phenotype - abnormal iron homeostasis
Debug Stats
  • ### Total Build Time: 53 ms 22.773 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 378 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 456 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 1.020 KB
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 576 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.926 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=46 ms Completed: 46 ms rowSize= 16.144 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.163 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal iron homeostasis MP:0005637
Definition (1)
anomaly in the processes involved in the maintenance of an internal equilibrium of iron that normally is a cofactor in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins; it is an essential component of enzymes such as catalase, peroxidase, and various cytochromes
Parents (2)
img abnormal ion homeostasis MP:0001765
img abnormal mineral homeostasis MP:0005636
Children (1)
img abnormal iron level MP:0001770
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img abnormal ion homeostasis MP:0001765
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img abnormal mineral homeostasis MP:0005636
Genes (79)

Species:
human : 79
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanTMPRSS6164656transmembrane protease, serine 6
Click here to display 43 evidence detail records.
HumanHFE2148738hemochromatosis type 2 (juvenile)
Click here to display 43 evidence detail records.
HumanSPIC121599Spi-C transcription factor (Spi-1/PU.1 related)
INFERRED
HumanBTBD9114781BTB (POZ) domain containing 9
INFERRED
HumanCYBRD179901cytochrome b reductase 1
INFERRED
HumanTTC7A57217tetratricopeptide repeat domain 7A
INFERRED
HumanANKH56172ANKH inorganic pyrophosphate transport regulator
INFERRED
HumanSLC39A455630solute carrier family 39 (zinc transporter), member 4
INFERRED
HumanSTEAP355240STEAP family member 3, metalloreductase
Click here to display 43 evidence detail records.
HumanEXOC654536exocyst complex component 6
Click here to display 43 evidence detail records.
HumanRASD151655RAS, dexamethasone-induced 1
Click here to display 43 evidence detail records.
HumanSLC25A3751312solute carrier family 25 (mitochondrial iron transporter), member 37
Click here to display 43 evidence detail records.
HumanSLC40A130061solute carrier family 40 (iron-regulated transporter), member 1
INFERRED
HumanSLC39A229986solute carrier family 39 (zinc transporter), member 2
INFERRED
HumanEIF2AK127102eukaryotic translation initiation factor 2-alpha kinase 1
Click here to display 43 evidence detail records.
HumanFBXL526234F-box and leucine-rich repeat protein 5
Click here to display 43 evidence detail records.
HumanABCB811194ATP-binding cassette, sub-family B (MDR/TAP), member 8
INFERRED
HumanHEPH9843hephaestin
Click here to display 43 evidence detail records.
HumanHYAL28692hyaluronoglucosaminidase 2
INFERRED
HumanPICALM8301phosphatidylinositol binding clathrin assembly protein
Click here to display 43 evidence detail records.
HumanUROS7390uroporphyrinogen III synthase
INFERRED
HumanTK17083thymidine kinase 1, soluble
INFERRED
HumanTFRC7037transferrin receptor (p90, CD71)
Click here to display 43 evidence detail records.
HumanTFR27036transferrin receptor 2
Click here to display 43 evidence detail records.
HumanTF7018transferrin
Click here to display 43 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005637abnormal iron homeostasis0self