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Details
Link-It Detail - Jax Mouse Phenotype - increased circulating potassium level
Debug Stats
  • ### Total Build Time: 28 ms 16.365 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 402 bytes
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Jax Mouse Phenotype (1)
increased circulating potassium level MP:0005627
Definition (1)
greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle
Synonyms (1)
"hyperkalemia" EXACT
Parents (1)
img abnormal circulating potassium level MP:0002668
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating potassium level MP:0002668
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal circulating potassium level MP:0002668
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanWNK465266WNK lysine deficient protein kinase 4
Click here to display 27 evidence detail records.
HumanFXYD453828FXYD domain containing ion transport regulator 4
Click here to display 27 evidence detail records.
HumanWWOX51741WW domain containing oxidoreductase
Click here to display 27 evidence detail records.
HumanZBTB2026137zinc finger and BTB domain containing 20
Click here to display 27 evidence detail records.
HumanNEDD4L23327neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Click here to display 27 evidence detail records.
HumanTXNIP10628thioredoxin interacting protein
Click here to display 27 evidence detail records.
HumanSCNN1G6340sodium channel, non-voltage-gated 1, gamma subunit
Click here to display 27 evidence detail records.
HumanSCNN1B6338sodium channel, non-voltage-gated 1, beta subunit
Click here to display 27 evidence detail records.
HumanRYR16261ryanodine receptor 1 (skeletal)
Click here to display 27 evidence detail records.
HumanREN5972renin
Click here to display 27 evidence detail records.
HumanPOU3F35455POU class 3 homeobox 3
Click here to display 27 evidence detail records.
HumanPIK3C2A5286phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
Click here to display 27 evidence detail records.
HumanNR3C24306nuclear receptor subfamily 3, group C, member 2
Click here to display 27 evidence detail records.
HumanMC2R4158melanocortin 2 receptor (adrenocorticotropic hormone)
Click here to display 27 evidence detail records.
HumanCYP11B11584cytochrome P450, family 11, subfamily B, polypeptide 1
Click here to display 27 evidence detail records.
HumanCLN31201ceroid-lipofuscinosis, neuronal 3
Click here to display 27 evidence detail records.
HumanAR367androgen receptor
Click here to display 27 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005627increased circulating potassium level0self