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Details
Link-It Detail - Jax Mouse Phenotype - increased cardiac muscle contractility
Debug Stats
  • ### Total Build Time: 173 ms 22.857 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 404 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 439 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 206 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 592 bytes
  • CONCEPT_CHILDREN gt=8 ms Completed: 8 ms rowSize= 597 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=23 ms Completed: 23 ms rowSize= 2.931 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=117 ms Completed: 117 ms rowSize= 16.421 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.176 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased cardiac muscle contractility MP:0005599
Definition (1)
greater than the normal ability of the heart muscle to shorten or to develop increased tension, often measured by dP/dT max, fractional shortening (FS), velocity of circumferential fiber shortening (Vcfc), peak of aortic outflow velocity (PAV), and ventricular ejection fraction volume
Synonyms (1)
"increased peak of aortic outflow velocity (PAV)" NARROW
Parents (1)
img abnormal cardiac muscle contractility MP:0002972
Children (1)
img increased ventricle muscle contractility MP:0005600
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img muscle phenotype MP:00053696img abnormal cardiac muscle contractility MP:0002972
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053855img abnormal cardiac muscle contractility MP:0002972
Genes (29)

Species:
human : 29
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGATA5140628GATA binding protein 5
INFERRED
HumanC12orf557103chromosome 12 open reading frame 5
Click here to display 42 evidence detail records.
HumanKDM4A9682lysine (K)-specific demethylase 4A
Click here to display 42 evidence detail records.
HumanCSRP38048cysteine and glycine-rich protein 3 (cardiac LIM protein)
Click here to display 42 evidence detail records.
HumanSLC8A16546solute carrier family 8 (sodium/calcium exchanger), member 1
INFERRED
HumanSFRP26423secreted frizzled-related protein 2
Click here to display 42 evidence detail records.
HumanRAF15894v-raf-1 murine leukemia viral oncogene homolog 1
Click here to display 42 evidence detail records.
HumanPTEN5728phosphatase and tensin homolog
Click here to display 42 evidence detail records.
HumanPLN5350phospholamban
Click here to display 42 evidence detail records.
HumanFXYD15348FXYD domain containing ion transport regulator 1
Click here to display 42 evidence detail records.
HumanPLAU5328plasminogen activator, urokinase
INFERRED
HumanPIK3CG5294phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Click here to display 42 evidence detail records.
HumanPDC5132phosducin
INFERRED
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
Click here to display 42 evidence detail records.
HumanNOS14842nitric oxide synthase 1 (neuronal)
Click here to display 42 evidence detail records.
HumanMYH64624myosin, heavy chain 6, cardiac muscle, alpha
Click here to display 42 evidence detail records.
HumanMYBPC34607myosin binding protein C, cardiac
Click here to display 42 evidence detail records.
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
INFERRED
HumanIGF13479insulin-like growth factor 1 (somatomedin C)
INFERRED
HumanHPRT13251hypoxanthine phosphoribosyltransferase 1
Click here to display 42 evidence detail records.
HumanFKBP1B2281FK506 binding protein 1B, 12.6 kDa
INFERRED
HumanCYP19A11588cytochrome P450, family 19, subfamily A, polypeptide 1
Click here to display 42 evidence detail records.
HumanBRAF673v-raf murine sarcoma viral oncogene homolog B
Click here to display 42 evidence detail records.
HumanBNIP3L665BCL2/adenovirus E1B 19kDa interacting protein 3-like
Click here to display 42 evidence detail records.
HumanATP1A1476ATPase, Na+/K+ transporting, alpha 1 polypeptide
Click here to display 42 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005599increased cardiac muscle contractility0self