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Details
Link-It Detail - Jax Mouse Phenotype - decreased susceptibility to type I hypersensitivity reaction
Debug Stats
  • ### Total Build Time: 65 ms 25.017 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 448 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 450 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 197 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 1.036 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=16 ms Completed: 16 ms rowSize= 4.277 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=39 ms Completed: 39 ms rowSize= 17.284 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.197 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased susceptibility to type I hypersensitivity reaction MP:0005597
Definition (1)
less likelihood or resistance to developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Synonyms (1)
"decreased susceptibility to anaphylaxis" EXACT
Parents (2)
img decreased acute inflammation MP:0005087
img abnormal type I hypersensitivity reaction MP:0002531
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img decreased acute inflammation MP:0005087
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal type I hypersensitivity reaction MP:0002531
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal type I hypersensitivity reaction MP:0002531
Genes (28)

Species:
human : 28
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 38 evidence detail records.
HumanTICAM1148022toll-like receptor adaptor molecule 1
Click here to display 38 evidence detail records.
HumanORAI184876ORAI calcium release-activated calcium modulator 1
Click here to display 38 evidence detail records.
HumanCYSLTR257105cysteinyl leukotriene receptor 2
Click here to display 38 evidence detail records.
HumanCYSLTR110800cysteinyl leukotriene receptor 1
Click here to display 38 evidence detail records.
HumanGAB29846GRB2-associated binding protein 2
Click here to display 38 evidence detail records.
HumanCCRL29034chemokine (C-C motif) receptor-like 2
Click here to display 38 evidence detail records.
HumanVIPR27434vasoactive intestinal peptide receptor 2
Click here to display 38 evidence detail records.
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
Click here to display 38 evidence detail records.
HumanSUV39H16839suppressor of variegation 3-9 homolog 1 (Drosophila)
Click here to display 38 evidence detail records.
HumanSTXBP26813syntaxin binding protein 2
Click here to display 38 evidence detail records.
HumanSTIM16786stromal interaction molecule 1
Click here to display 38 evidence detail records.
HumanSERPINB46318serpin peptidase inhibitor, clade B (ovalbumin), member 4
Click here to display 38 evidence detail records.
HumanPTPRC5788protein tyrosine phosphatase, receptor type, C
Click here to display 38 evidence detail records.
HumanMCL14170myeloid cell leukemia sequence 1 (BCL2-related)
Click here to display 38 evidence detail records.
HumanLTA4H4048leukotriene A4 hydrolase
Click here to display 38 evidence detail records.
HumanLBP3929lipopolysaccharide binding protein
Click here to display 38 evidence detail records.
HumanGNA112767guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Click here to display 38 evidence detail records.
HumanFCGR2A2212Fc fragment of IgG, low affinity IIa, receptor (CD32)
Click here to display 38 evidence detail records.
HumanMS4A22206membrane-spanning 4-domains, subfamily A, member 2
Click here to display 38 evidence detail records.
HumanECM11893extracellular matrix protein 1
Click here to display 38 evidence detail records.
HumanCSF2RB1439colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Click here to display 38 evidence detail records.
HumanCPA31359carboxypeptidase A3 (mast cell)
Click here to display 38 evidence detail records.
HumanCCR61235chemokine (C-C motif) receptor 6
Click here to display 38 evidence detail records.
HumanCD81975CD81 molecule
Click here to display 38 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005597decreased susceptibility to type I hypersensitivity reaction0self