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Details
Link-It Detail - Jax Mouse Phenotype - choroidal neovascularization
Debug Stats
  • ### Total Build Time: 131 ms 57.176 KB
  • CONCEPT_NAME gt=5 ms Completed: 4 ms rowSize= 384 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 305 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 1.037 KB
  • CONCEPT_CHILDREN gt=22 ms Completed: 22 ms rowSize= 1.094 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=47 ms Completed: 47 ms rowSize= 5.636 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=39 ms Completed: 39 ms rowSize= 47.426 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
choroidal neovascularization MP:0005546
Definition (1)
new, abnormal, vessel development of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera
Parents (2)
img abnormal choroid vasculature morphology MP:0006237
img pathological neovascularization MP:0003711
Children (2)
img decreased susceptibility to induced choroidal neovascularization MP:0003434
img increased susceptibility to induced choroid neovascularization MP:0011557
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img vision/eye phenotype MP:00053919img abnormal choroid vasculature morphology MP:0006237
img mammalian phenotype MP:0000001img vision/eye phenotype MP:00053918img abnormal choroid vasculature morphology MP:0006237
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053856img abnormal choroid vasculature morphology MP:0006237
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053858img pathological neovascularization MP:0003711
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
img Jax MP, Pubmed Id: 18172119, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 20880997, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 12972764, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 21844367, MOUSE PHENOTYPE ID: MGI:5285548
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:98259
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:106185
img Jax MP, Pubmed Id: 19339747, MOUSE PHENOTYPE ID: MGI:88338
img Jax MP, Pubmed Id: 17237428, MOUSE PHENOTYPE ID: MGI:109177
img Jax MP, Pubmed Id: 17652758, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
HumanADAM158751ADAM metallopeptidase domain 15
INFERRED
HumanVLDLR7436very low density lipoprotein receptor
img Jax MP, Pubmed Id: 17237428, MOUSE PHENOTYPE ID: MGI:109177
img Jax MP, Pubmed Id: 18172119, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 20880997, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 12972764, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 17652758, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:106185
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:98259
img Jax MP, Pubmed Id: 19339747, MOUSE PHENOTYPE ID: MGI:88338
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 21844367, MOUSE PHENOTYPE ID: MGI:5285548
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
HumanCCL136357chemokine (C-C motif) ligand 13
img Jax MP, Pubmed Id: 17652758, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 19339747, MOUSE PHENOTYPE ID: MGI:88338
img Jax MP, Pubmed Id: 20880997, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 18172119, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:98259
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:106185
img Jax MP, Pubmed Id: 21844367, MOUSE PHENOTYPE ID: MGI:5285548
img Jax MP, Pubmed Id: 17237428, MOUSE PHENOTYPE ID: MGI:109177
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 12972764, MOUSE PHENOTYPE ID: MGI:98935
HumanPLG5340plasminogen
INFERRED
HumanPLAU5328plasminogen activator, urokinase
INFERRED
HumanPLAT5327plasminogen activator, tissue
INFERRED
HumanNOS24843nitric oxide synthase 2, inducible
INFERRED
HumanNOS14842nitric oxide synthase 1 (neuronal)
INFERRED
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
INFERRED
HumanITGB23689integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
INFERRED
HumanIL103586interleukin 10
INFERRED
HumanICAM13383intercellular adhesion molecule 1
INFERRED
HumanCX3CR11524chemokine (C-X3-C motif) receptor 1
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:106185
img Jax MP, Pubmed Id: 12972764, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 18172119, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 17652758, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 19339747, MOUSE PHENOTYPE ID: MGI:88338
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:98259
img Jax MP, Pubmed Id: 21844367, MOUSE PHENOTYPE ID: MGI:5285548
img Jax MP, Pubmed Id: 17237428, MOUSE PHENOTYPE ID: MGI:109177
img Jax MP, Pubmed Id: 20880997, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
HumanCD44960CD44 molecule (Indian blood group)
img Jax MP, Pubmed Id: 17237428, MOUSE PHENOTYPE ID: MGI:109177
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 20880997, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 12972764, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 18172119, MOUSE PHENOTYPE ID: MGI:98935
img Jax MP, Pubmed Id: 17652758, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 17909628, MOUSE PHENOTYPE ID: MGI:1333815
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:98259
img Jax MP, Pubmed Id: 14566334, MOUSE PHENOTYPE ID: MGI:106185
img Jax MP, Pubmed Id: 21844367, MOUSE PHENOTYPE ID: MGI:5285548
img Jax MP, Pubmed Id: 19339747, MOUSE PHENOTYPE ID: MGI:88338
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005546choroidal neovascularization0self