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Details
Link-It Detail - Jax Mouse Phenotype - abnormal lens development
Debug Stats
  • ### Total Build Time: 91 ms 23.557 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 378 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 248 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.016 KB
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 1.456 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.898 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=81 ms Completed: 81 ms rowSize= 16.268 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.163 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal lens development MP:0005545
Definition (1)
aberrant formation of the transparent structure of the eye responsible for focusing light rays
Parents (2)
img abnormal lens morphology MP:0001303
img abnormal eye development MP:0001286
Children (3)
img fused cornea and lens MP:0001307
img vacuolated lens MP:0011697
img abnormal lens induction MP:0001288
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img vision/eye phenotype MP:00053916img abnormal lens morphology MP:0001303
img mammalian phenotype MP:0000001img vision/eye phenotype MP:00053915img abnormal eye development MP:0001286
Genes (51)

Species:
human : 51
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SpeciesGeneGeneIdGene NameEvidence
HumanVSX2338917visual system homeobox 2
Click here to display 72 evidence detail records.
HumanPYGO290780pygopus homolog 2 (Drosophila)
Click here to display 72 evidence detail records.
HumanZNRF384133zinc and ring finger 3
Click here to display 72 evidence detail records.
HumanCOL18A180781collagen, type XVIII, alpha 1
Click here to display 72 evidence detail records.
HumanTWSG157045twisted gastrulation homolog 1 (Drosophila)
INFERRED
HumanRAB2351715RAB23, member RAS oncogene family
INFERRED
HumanHIPK228996homeodomain interacting protein kinase 2
INFERRED
HumanGRIP123426glutamate receptor interacting protein 1
Click here to display 72 evidence detail records.
HumanPDS5A23244PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
Click here to display 72 evidence detail records.
HumanMAB21L210586mab-21-like 2 (C. elegans)
Click here to display 72 evidence detail records.
HumanSEP15940315 kDa selenoprotein
INFERRED
HumanLHX29355LIM homeobox 2
Click here to display 72 evidence detail records.
HumanBCAR38412breast cancer anti-estrogen resistance 3
INFERRED
HumanTGFB27042transforming growth factor, beta 2
INFERRED
HumanTFAP2A7020transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Click here to display 72 evidence detail records.
HumanADAM176868ADAM metallopeptidase domain 17
INFERRED
HumanSOX16656SRY (sex determining region Y)-box 1
Click here to display 72 evidence detail records.
HumanSMO6608smoothened, frizzled family receptor
Click here to display 72 evidence detail records.
HumanSIX36496SIX homeobox 3
Click here to display 72 evidence detail records.
HumanRB15925retinoblastoma 1
Click here to display 72 evidence detail records.
HumanPROX15629prospero homeobox 1
Click here to display 72 evidence detail records.
HumanMED15469mediator complex subunit 1
Click here to display 72 evidence detail records.
HumanPOU2F15451POU class 2 homeobox 1
INFERRED
HumanPITX35309paired-like homeodomain 3
Click here to display 72 evidence detail records.
HumanPITX25308paired-like homeodomain 2
Click here to display 72 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005545abnormal lens development0self