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Details
Link-It Detail - Jax Mouse Phenotype - abnormal mesangial cell morphology
Debug Stats
  • ### Total Build Time: 32 ms 75.707 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 635 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 197 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 595 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.923 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 1.592 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=18 ms Completed: 18 ms rowSize= 69.096 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal mesangial cell morphology MP:0005327
Definition (1)
any structural anomaly of the modified smooth muscle cells that are interposed between endothelial cells and the basement membrane in the central or stalk region of the capillary tuft of the renal glomerulus, which regulate blood flow by their contractile activity, and secrete extracellular matrix, prostaglandins, and cytokines; mesangial cells also have phagocytic activity, removing proteins and other molecules trapped in the glomerular basement membrane or filtration barrier
Synonyms (1)
"abnormal intraglomerular mesangial cell" EXACT
Parents (1)
img abnormal glomerular mesangium morphology MP:0011339
Children (4)
img mesangial cell hypoplasia MP:0011428
img mesangial cell interposition MP:0011512
img absent mesangial cell MP:0011429
img mesangial cell hyperplasia MP:0011427
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053679img abnormal glomerular mesangium morphology MP:0011339
Genes (39)

Species:
human : 39
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanKIRREL55243kin of IRRE like (Drosophila)
INFERRED
HumanEHD430844EH-domain containing 4
INFERRED
HumanCD2AP23607CD2-associated protein
INFERRED
HumanTNFRSF13B23495tumor necrosis factor receptor superfamily, member 13B
INFERRED
HumanTRAF3IP210758TRAF3 interacting protein 2
INFERRED
HumanMTA29219metastasis associated 1 family, member 2
INFERRED
HumanTNFSF148740tumor necrosis factor (ligand) superfamily, member 14
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 11124809, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 12039984, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 11239463, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 10625553, MOUSE PHENOTYPE ID: MGI:105382
img Jax MP, Pubmed Id: 16498405, MOUSE PHENOTYPE ID: MGI:1347481
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:2654007
img Jax MP, Pubmed Id: 16987502, MOUSE PHENOTYPE ID: MGI:1355317
img Jax MP, Pubmed Id: 10077614, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 17968950, MOUSE PHENOTYPE ID: MGI:3843669
img Jax MP, Pubmed Id: 21881212, MOUSE PHENOTYPE ID: MGI:2450863
img Jax MP, Pubmed Id: 19797313, MOUSE PHENOTYPE ID: MGI:98968
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
INFERRED
HumanWT17490Wilms tumor 1
img Jax MP, Pubmed Id: 16498405, MOUSE PHENOTYPE ID: MGI:1347481
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:2654007
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 10625553, MOUSE PHENOTYPE ID: MGI:105382
img Jax MP, Pubmed Id: 17968950, MOUSE PHENOTYPE ID: MGI:3843669
img Jax MP, Pubmed Id: 12039984, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 10077614, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 16987502, MOUSE PHENOTYPE ID: MGI:1355317
img Jax MP, Pubmed Id: 21881212, MOUSE PHENOTYPE ID: MGI:2450863
img Jax MP, Pubmed Id: 19797313, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 11239463, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 11124809, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
HumanWAS7454Wiskott-Aldrich syndrome
INFERRED
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
INFERRED
HumanVEGFA7422vascular endothelial growth factor A
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 10077614, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:2654007
img Jax MP, Pubmed Id: 16987502, MOUSE PHENOTYPE ID: MGI:1355317
img Jax MP, Pubmed Id: 12039984, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 10625553, MOUSE PHENOTYPE ID: MGI:105382
img Jax MP, Pubmed Id: 11124809, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 21881212, MOUSE PHENOTYPE ID: MGI:2450863
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 17968950, MOUSE PHENOTYPE ID: MGI:3843669
img Jax MP, Pubmed Id: 19797313, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 11239463, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 16498405, MOUSE PHENOTYPE ID: MGI:1347481
HumanSYK6850spleen tyrosine kinase
INFERRED
HumanPKN15585protein kinase N1
INFERRED
HumanPKHD15314polycystic kidney and hepatic disease 1 (autosomal recessive)
INFERRED
HumanPDGFRB5159platelet-derived growth factor receptor, beta polypeptide
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 11239463, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 21881212, MOUSE PHENOTYPE ID: MGI:2450863
img Jax MP, Pubmed Id: 10077614, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 17968950, MOUSE PHENOTYPE ID: MGI:3843669
img Jax MP, Pubmed Id: 12039984, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 16498405, MOUSE PHENOTYPE ID: MGI:1347481
img Jax MP, Pubmed Id: 19797313, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 10625553, MOUSE PHENOTYPE ID: MGI:105382
img Jax MP, Pubmed Id: 16987502, MOUSE PHENOTYPE ID: MGI:1355317
img Jax MP, Pubmed Id: 11124809, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:2654007
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
HumanPDGFB5155platelet-derived growth factor beta polypeptide
INFERRED
HumanNPHS14868nephrosis 1, congenital, Finnish type (nephrin)
INFERRED
HumanNOTCH24853notch 2
INFERRED
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
INFERRED
HumanNFE2L24780nuclear factor, erythroid 2-like 2
INFERRED
HumanLYN4067v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
INFERRED
HumanLCAT3931lecithin-cholesterol acyltransferase
INFERRED
HumanLAMA53911laminin, alpha 5
img Jax MP, Pubmed Id: 17968950, MOUSE PHENOTYPE ID: MGI:3843669
img Jax MP, Pubmed Id: 16987502, MOUSE PHENOTYPE ID: MGI:1355317
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 21881212, MOUSE PHENOTYPE ID: MGI:2450863
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 16498405, MOUSE PHENOTYPE ID: MGI:1347481
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 10625553, MOUSE PHENOTYPE ID: MGI:105382
img Jax MP, Pubmed Id: 18040647, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 10077614, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 12039984, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 11124809, MOUSE PHENOTYPE ID: MGI:97531
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:2654007
img Jax MP, Pubmed Id: 19797313, MOUSE PHENOTYPE ID: MGI:98968
img Jax MP, Pubmed Id: 11239463, MOUSE PHENOTYPE ID: MGI:97531
HumanIFNG3458interferon, gamma
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005327abnormal mesangial cell morphology0self