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Details
Link-It Detail - Jax Mouse Phenotype - increased circulating cholesterol level
Debug Stats
  • ### Total Build Time: 4,207 ms 26.956 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 406 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 436 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 203 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 1.032 KB
  • CONCEPT_CHILDREN gt=11 ms Completed: 11 ms rowSize= 1.525 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=10 ms Completed: 10 ms rowSize= 4.297 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=4,161 ms Completed: 4.161 Seconds rowSize= 17.760 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.177 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
increased circulating cholesterol level MP:0005178
Definition (1)
greater than the normal amount in the blood of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues
Synonyms (1)
"increased total circulating cholesterol level" EXACT
Parents (2)
img abnormal circulating cholesterol level MP:0000180
img increased cholesterol level MP:0003982
Children (3)
img increased circulating VLDL cholesterol level MP:0005145
img increased circulating LDL cholesterol level MP:0000182
img increased circulating HDL cholesterol level MP:0001556
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal circulating cholesterol level MP:0000180
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating cholesterol level MP:0000180
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img increased cholesterol level MP:0003982
Genes (146)

Species:
human : 146
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Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 390 evidence detail records.
HumanFFAR4338557free fatty acid receptor 4
Click here to display 390 evidence detail records.
HumanGPIHBP1338328glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
Click here to display 390 evidence detail records.
HumanAQP11282679aquaporin 11
INFERRED
HumanPCSK9255738proprotein convertase subtilisin/kexin type 9
INFERRED
HumanRICTOR253260RPTOR independent companion of MTOR, complex 2
Click here to display 390 evidence detail records.
HumanGPBAR1151306G protein-coupled bile acid receptor 1
Click here to display 390 evidence detail records.
HumanUHMK1127933U2AF homology motif (UHM) kinase 1
Click here to display 390 evidence detail records.
HumanAPOA5116519apolipoprotein A-V
INFERRED
HumanANGPTL683854angiopoietin-like 6
Click here to display 390 evidence detail records.
HumanPLVAP83483plasmalemma vesicle associated protein
Click here to display 390 evidence detail records.
HumanFTO79068fat mass and obesity associated
Click here to display 390 evidence detail records.
HumanLMF164788lipase maturation factor 1
Click here to display 390 evidence detail records.
HumanNCEH157552neutral cholesterol ester hydrolase 1
Click here to display 390 evidence detail records.
HumanPDSS257107prenyl (decaprenyl) diphosphate synthase, subunit 2
Click here to display 390 evidence detail records.
HumanKDM3A55818lysine (K)-specific demethylase 3A
Click here to display 390 evidence detail records.
HumanHIF1AN55662hypoxia inducible factor 1, alpha subunit inhibitor
Click here to display 390 evidence detail records.
HumanUACA55075uveal autoantigen with coiled-coil domains and ankyrin repeats
Click here to display 390 evidence detail records.
HumanBCMO153630beta-carotene 15,15'-monooxygenase 1
Click here to display 390 evidence detail records.
HumanADIPOR151094adiponectin receptor 1
Click here to display 390 evidence detail records.
HumanRRM2B50484ribonucleotide reductase M2 B (TP53 inducible)
Click here to display 390 evidence detail records.
HumanTBX2130009T-box 21
Click here to display 390 evidence detail records.
HumanSLC2A829988solute carrier family 2 (facilitated glucose transporter), member 8
Click here to display 390 evidence detail records.
HumanSEC61A129927Sec61 alpha 1 subunit (S. cerevisiae)
Click here to display 390 evidence detail records.
HumanSLCO1B328234solute carrier organic anion transporter family, member 1B3
Click here to display 390 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005178increased circulating cholesterol level0self