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Details
Link-It Detail - Jax Mouse Phenotype - abnormal blood-brain barrier function
Debug Stats
  • ### Total Build Time: 158 ms 20.602 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 402 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 350 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 1.033 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 2.931 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=140 ms Completed: 140 ms rowSize= 14.576 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.175 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal blood-brain barrier function MP:0005167
Definition (1)
anomaly in the function of the group of barriers and transport systems in the brain capillary endothelium that controls the entrance of substances into the brain extracellular space from the blood
Parents (2)
img abnormal nervous system physiology MP:0003633
img abnormal blood vessel physiology MP:0000249
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036314img abnormal nervous system physiology MP:0003633
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053855img abnormal blood vessel physiology MP:0000249
Genes (24)

Species:
human : 24
SpeciesGeneGeneIdGene NameEvidence
HumanTNFRSF1955504tumor necrosis factor receptor superfamily, member 19
Click here to display 35 evidence detail records.
HumanNOX450507NADPH oxidase 4
Click here to display 35 evidence detail records.
HumanTNFRSF2127242tumor necrosis factor receptor superfamily, member 21
Click here to display 35 evidence detail records.
HumanGPR12425960G protein-coupled receptor 124
Click here to display 35 evidence detail records.
HumanHRH311255histamine receptor H3
Click here to display 35 evidence detail records.
HumanRAMP210266receptor (G protein-coupled) activity modifying protein 2
Click here to display 35 evidence detail records.
HumanABCC410257ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Click here to display 35 evidence detail records.
HumanVWF7450von Willebrand factor
Click here to display 35 evidence detail records.
HumanCLDN57122claudin 5
Click here to display 35 evidence detail records.
HumanPTAFR5724platelet-activating factor receptor
Click here to display 35 evidence detail records.
HumanABCB15243ATP-binding cassette, sub-family B (MDR/TAP), member 1
Click here to display 35 evidence detail records.
HumanPDGFB5155platelet-derived growth factor beta polypeptide
Click here to display 35 evidence detail records.
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
Click here to display 35 evidence detail records.
HumanNOS14842nitric oxide synthase 1 (neuronal)
Click here to display 35 evidence detail records.
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
Click here to display 35 evidence detail records.
HumanIL1B3553interleukin 1, beta
Click here to display 35 evidence detail records.
HumanNR3C12908nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Click here to display 35 evidence detail records.
HumanGFAP2670glial fibrillary acidic protein
Click here to display 35 evidence detail records.
HumanGALC2581galactosylceramidase
Click here to display 35 evidence detail records.
HumanCTNNB11499catenin (cadherin-associated protein), beta 1, 88kDa
Click here to display 35 evidence detail records.
HumanCLCN21181chloride channel, voltage-sensitive 2
Click here to display 35 evidence detail records.
HumanAQP4361aquaporin 4
Click here to display 35 evidence detail records.
HumanAPOE348apolipoprotein E
Click here to display 35 evidence detail records.
HumanAGT183angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Click here to display 35 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005167abnormal blood-brain barrier function0self