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Details
Link-It Detail - Jax Mouse Phenotype - decreased cardiac muscle contractility
Debug Stats
  • ### Total Build Time: 1,511 ms 25.095 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 404 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 436 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 218 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 1.033 KB
  • CONCEPT_CHILDREN gt=6 ms Completed: 6 ms rowSize= 597 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 4.265 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=1,484 ms Completed: 1.484 Seconds rowSize= 16.860 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.176 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased cardiac muscle contractility MP:0005140
Definition (1)
inability or reduced ability of the heart muscle to shorten or to develop increased tension, often measured by dP/dT max, fractional shortening (FS), velocity of circumferential fiber shortening (Vcfc), peak of aortic outflow velocity (PAV), and ventricular ejection fraction volume
Synonyms (1)
"reduced velocity of circumferential fiber shortening (Vcfc)" NARROW
Parents (2)
img abnormal cardiac muscle contractility MP:0002972
img impaired muscle contractility MP:0000738
Children (1)
img decreased ventricle muscle contractility MP:0005598
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img muscle phenotype MP:00053696img abnormal cardiac muscle contractility MP:0002972
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053855img abnormal cardiac muscle contractility MP:0002972
img mammalian phenotype MP:0000001img muscle phenotype MP:00053696img impaired muscle contractility MP:0000738
Genes (165)

Species:
human : 165
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPLIN5440503perilipin 5
Click here to display 224 evidence detail records.
HumanXIRP1165904xin actin-binding repeat containing 1
Click here to display 224 evidence detail records.
HumanMYLK391807myosin light chain kinase 3
Click here to display 224 evidence detail records.
HumanTRIM6384676tripartite motif containing 63, E3 ubiquitin protein ligase
Click here to display 224 evidence detail records.
HumanHOPX84525HOP homeobox
Click here to display 224 evidence detail records.
HumanACE259272angiotensin I converting enzyme 2
Click here to display 224 evidence detail records.
HumanHEG157493heart development protein with EGF-like domains 1
INFERRED
HumanPNPLA257104patatin-like phospholipase domain containing 2
INFERRED
HumanTBX2057057T-box 20
INFERRED
HumanLIMS255679LIM and senescent cell antigen-like domains 2
Click here to display 224 evidence detail records.
HumanEGLN154583egl-9 family hypoxia-inducible factor 1
INFERRED
HumanDGCR854487DGCR8 microprocessor complex subunit
INFERRED
HumanMYOZ251778myozenin 2
Click here to display 224 evidence detail records.
HumanPLCE151196phospholipase C, epsilon 1
Click here to display 224 evidence detail records.
HumanABHD551099abhydrolase domain containing 5
INFERRED
HumanIRX450805iroquois homeobox 4
INFERRED
HumanNOX450507NADPH oxidase 4
Click here to display 224 evidence detail records.
HumanKLF1528999Kruppel-like factor 15
INFERRED
HumanHSPB826353heat shock 22kDa protein 8
INFERRED
HumanHEY223493hairy/enhancer-of-split related with YRPW motif 2
Click here to display 224 evidence detail records.
HumanZFPM223414zinc finger protein, FOG family member 2
Click here to display 224 evidence detail records.
HumanNEDD4L23327neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Click here to display 224 evidence detail records.
HumanABCB811194ATP-binding cassette, sub-family B (MDR/TAP), member 8
Click here to display 224 evidence detail records.
HumanFSTL111167follistatin-like 1
Click here to display 224 evidence detail records.
HumanATE111101arginyltransferase 1
Click here to display 224 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005140decreased cardiac muscle contractility0self