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Details
Link-It Detail - Jax Mouse Phenotype - decreased B cell proliferation
Debug Stats
  • ### Total Build Time: 369 ms 31.490 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 388 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 251 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 584 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 10.979 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=359 ms Completed: 359 ms rowSize= 17.813 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.168 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased B cell proliferation MP:0005093
Definition (1)
absent or reduced expansion rate of the B cell population by cell division in response to stimuli
Synonyms (1)
"defective B-cell proliferation" EXACT
Parents (1)
img abnormal B cell proliferation MP:0005153
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal B cell proliferation MP:0005153
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal B cell proliferation MP:0005153
img mammalian phenotype MP:0000001img immune system phenotype MP:000538712img abnormal B cell proliferation MP:0005153
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539713img abnormal B cell proliferation MP:0005153
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539712img abnormal B cell proliferation MP:0005153
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal B cell proliferation MP:0005153
img mammalian phenotype MP:0000001img cellular phenotype MP:000538410img abnormal B cell proliferation MP:0005153
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal B cell proliferation MP:0005153
Genes (85)

Species:
human : 85
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SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
Click here to display 152 evidence detail records.
HumanPIM3415116pim-3 oncogene
Click here to display 152 evidence detail records.
HumanTAB3257397TGF-beta activated kinase 1/MAP3K7 binding protein 3
Click here to display 152 evidence detail records.
HumanPIK3AP1118788phosphoinositide-3-kinase adaptor protein 1
Click here to display 152 evidence detail records.
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
Click here to display 152 evidence detail records.
HumanTIRAP114609toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Click here to display 152 evidence detail records.
HumanSPPL2A84888signal peptide peptidase like 2A
Click here to display 152 evidence detail records.
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
Click here to display 152 evidence detail records.
HumanCARD1184433caspase recruitment domain family, member 11
Click here to display 152 evidence detail records.
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
Click here to display 152 evidence detail records.
HumanDCLRE1C64421DNA cross-link repair 1C
Click here to display 152 evidence detail records.
HumanMAVS57506mitochondrial antiviral signaling protein
Click here to display 152 evidence detail records.
HumanPELI157162pellino E3 ubiquitin protein ligase 1
Click here to display 152 evidence detail records.
HumanPPP2R3C55012protein phosphatase 2, regulatory subunit B'', gamma
Click here to display 152 evidence detail records.
HumanIRAK451135interleukin-1 receptor-associated kinase 4
Click here to display 152 evidence detail records.
HumanBLNK29760B-cell linker
Click here to display 152 evidence detail records.
HumanDAPP127071dual adaptor of phosphotyrosine and 3-phosphoinositides
Click here to display 152 evidence detail records.
HumanLY9623643lymphocyte antigen 96
Click here to display 152 evidence detail records.
HumanRRAS222800related RAS viral (r-ras) oncogene homolog 2
Click here to display 152 evidence detail records.
HumanSEMA4D10507sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Click here to display 152 evidence detail records.
HumanVAV310451vav 3 guanine nucleotide exchange factor
Click here to display 152 evidence detail records.
HumanIKZF110320IKAROS family zinc finger 1 (Ikaros)
Click here to display 152 evidence detail records.
HumanARHGEF69459Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Click here to display 152 evidence detail records.
HumanLY869450lymphocyte antigen 86
Click here to display 152 evidence detail records.
HumanARHGEF19138Rho guanine nucleotide exchange factor (GEF) 1
Click here to display 152 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005093decreased B cell proliferation0self