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Details
Link-It Detail - Jax Mouse Phenotype - impaired natural killer cell mediated cytotoxicity
Debug Stats
  • ### Total Build Time: 450 ms 23.135 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 428 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 340 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 185 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 605 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=18 ms Completed: 18 ms rowSize= 2.955 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=404 ms Completed: 404 ms rowSize= 17.318 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.188 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
impaired natural killer cell mediated cytotoxicity MP:0005070
Definition (1)
impaired ability of directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors
Synonyms (1)
"defective NK cell cytolysis" EXACT
Parents (1)
img abnormal natural killer cell mediated cytotoxicity MP:0011719
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal natural killer cell mediated cytotoxicity MP:0011719
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal natural killer cell mediated cytotoxicity MP:0011719
Genes (52)

Species:
human : 52
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanKLRC4-KLRK1100528032
Click here to display 94 evidence detail records.
HumanTICAM1148022toll-like receptor adaptor molecule 1
Click here to display 94 evidence detail records.
HumanRNF19B127544ring finger protein 19B
Click here to display 94 evidence detail records.
HumanSH2D1B117157SH2 domain containing 1B
Click here to display 94 evidence detail records.
HumanFOXQ194234forkhead box Q1
Click here to display 94 evidence detail records.
HumanSLAMF757823SLAM family member 7
Click here to display 94 evidence detail records.
HumanTLR954106toll-like receptor 9
Click here to display 94 evidence detail records.
HumanCD24451744CD244 molecule, natural killer cell receptor 2B4
Click here to display 94 evidence detail records.
HumanIL21R50615interleukin 21 receptor
Click here to display 94 evidence detail records.
HumanTBX2130009T-box 21
Click here to display 94 evidence detail records.
HumanKLRK122914killer cell lectin-like receptor subfamily K, member 1
Click here to display 94 evidence detail records.
HumanHCST10870hematopoietic cell signal transducer
Click here to display 94 evidence detail records.
HumanCD22610666CD226 molecule
Click here to display 94 evidence detail records.
HumanNCR19437natural cytotoxicity triggering receptor 1
Click here to display 94 evidence detail records.
HumanIL18R18809interleukin 18 receptor 1
Click here to display 94 evidence detail records.
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
Click here to display 94 evidence detail records.
HumanSTX118676syntaxin 11
Click here to display 94 evidence detail records.
HumanVAV17409vav 1 guanine nucleotide exchange factor
Click here to display 94 evidence detail records.
HumanTYROBP7305TYRO protein tyrosine kinase binding protein
Click here to display 94 evidence detail records.
HumanSTAT5B6777signal transducer and activator of transcription 5B
Click here to display 94 evidence detail records.
HumanSTAT5A6776signal transducer and activator of transcription 5A
Click here to display 94 evidence detail records.
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
Click here to display 94 evidence detail records.
HumanRAG15896recombination activating gene 1
Click here to display 94 evidence detail records.
HumanRAB27A5873RAB27A, member RAS oncogene family
Click here to display 94 evidence detail records.
HumanPRKDC5591protein kinase, DNA-activated, catalytic polypeptide
Click here to display 94 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005070impaired natural killer cell mediated cytotoxicity0self