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Details
Link-It Detail - Jax Mouse Phenotype - abnormal MHC II cell surface expression on macrophages
Debug Stats
  • ### Total Build Time: 25 ms 55.312 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 436 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 264 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.051 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=10 ms Completed: 10 ms rowSize= 9.709 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=10 ms Completed: 10 ms rowSize= 42.525 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.191 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal MHC II cell surface expression on macrophages MP:0005040
Definition (1)
anomaly in the ability of macrophages to express major histocompatibility complex class II at the cell surface
Parents (2)
img abnormal level of surface class II molecules MP:0005042
img abnormal macrophage antigen presentation MP:0002454
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal level of surface class II molecules MP:0005042
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal level of surface class II molecules MP:0005042
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal level of surface class II molecules MP:0005042
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal level of surface class II molecules MP:0005042
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal macrophage antigen presentation MP:0002454
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal macrophage antigen presentation MP:0002454
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal macrophage antigen presentation MP:0002454
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
HumanRFX55993regulatory factor X, 5 (influences HLA class II expression)
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
HumanCIITA4261class II, major histocompatibility complex, transactivator
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
HumanIFNG3458interferon, gamma
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
HumanHLA-DQA13117
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
HumanCSF21437colony stimulating factor 2 (granulocyte-macrophage)
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005040abnormal MHC II cell surface expression on macrophages0self