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Details
Link-It Detail - Jax Mouse Phenotype - abnormal MHC II cell surface expression on macrophages
Debug Stats
  • ### Total Build Time: 39 ms 55.318 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 436 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 264 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=10 ms Completed: 10 ms rowSize= 1.051 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 9.709 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=22 ms Completed: 22 ms rowSize= 42.531 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.191 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal MHC II cell surface expression on macrophages MP:0005040
Definition (1)
anomaly in the ability of macrophages to express major histocompatibility complex class II at the cell surface
Parents (2)
img abnormal macrophage antigen presentation MP:0002454
img abnormal level of surface class II molecules MP:0005042
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal macrophage antigen presentation MP:0002454
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal macrophage antigen presentation MP:0002454
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal macrophage antigen presentation MP:0002454
img mammalian phenotype MP:0000001img immune system phenotype MP:000538711img abnormal level of surface class II molecules MP:0005042
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal level of surface class II molecules MP:0005042
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal level of surface class II molecules MP:0005042
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal level of surface class II molecules MP:0005042
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
HumanRFX55993regulatory factor X, 5 (influences HLA class II expression)
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
HumanCIITA4261class II, major histocompatibility complex, transactivator
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
HumanIFNG3458interferon, gamma
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
HumanHLA-DQA13117
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
HumanCSF21437colony stimulating factor 2 (granulocyte-macrophage)
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
img Jax MP, Pubmed Id: 8456300, MOUSE PHENOTYPE ID: MGI:107656
img Jax MP, Pubmed Id: 16546098, MOUSE PHENOTYPE ID: MGI:109404
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 10684813, MOUSE PHENOTYPE ID: MGI:1339752
img Jax MP, Pubmed Id: 9491996, MOUSE PHENOTYPE ID: MGI:1858421
img Jax MP, Pubmed Id: 8624807, MOUSE PHENOTYPE ID: MGI:108445
img Jax MP, Pubmed Id: 10621974, MOUSE PHENOTYPE ID: MGI:95895
img Jax MP, Pubmed Id: 14670297, MOUSE PHENOTYPE ID: MGI:103063
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0005040abnormal MHC II cell surface expression on macrophages0self