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Details
Link-It Detail - Jax Mouse Phenotype - abnormal regulatory T cell morphology
Debug Stats
  • ### Total Build Time: 22 ms 44.140 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 402 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 600 bytes
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  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 35.251 KB
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Jax Mouse Phenotype (1)
abnormal regulatory T cell morphology MP:0004941
Definition (1)
any structural anomaly of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity; these may include T cells that express the CD8 transmembrane glycoprotein (CD8-positive T cells), those that express CD4 and CD25 (CD4-positive, CD25-positive regulatory T cells or Tregs) and other T cell types that have suppressor function
Synonyms (1)
"abnormal suppressor T lymphocyte morphology" EXACT
Parents (1)
img abnormal T cell morphology MP:0008037
Children (3)
img abnormal regulatory T cell number MP:0004972
img abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology MP:0008397
img abnormal CD8-positive, alpha-beta regulatory T cell morphology MP:0008398
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal T cell morphology MP:0008037
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal T cell morphology MP:0008037
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal T cell morphology MP:0008037
Genes (58)

Species:
human : 58
Page Size
Current 25
  Page 1 of 3
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanUSP17L29728405ubiquitin specific peptidase 17-like family member 29
INFERRED
HumanUSP17L28728400ubiquitin specific peptidase 17-like family member 28
INFERRED
HumanUSP17L27728393ubiquitin specific peptidase 17-like family member 27
INFERRED
HumanUSP17L5728386ubiquitin specific peptidase 17-like family member 5
INFERRED
HumanUSP17L26728379ubiquitin specific peptidase 17-like family member 26
INFERRED
HumanUSP17L25728373ubiquitin specific peptidase 17-like family member 25
INFERRED
HumanUSP17L24728369ubiquitin specific peptidase 17-like family member 24
INFERRED
HumanTHEMIS387357thymocyte selection associated
img Jax MP, Pubmed Id: 18725527, MOUSE PHENOTYPE ID: MGI:1261425
img Jax MP, Pubmed Id: 18725525, MOUSE PHENOTYPE ID: MGI:2177178
img Jax MP, Pubmed Id: 19597499, MOUSE PHENOTYPE ID: MGI:2443552
img Jax MP, Pubmed Id: 22177923, MOUSE PHENOTYPE ID: MGI:2443256
img Jax MP, Pubmed Id: 20072126, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 22908322, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 20133615, MOUSE PHENOTYPE ID: MGI:1335098
HumanRC3H1149041ring finger and CCCH-type domains 1
INFERRED
HumanCARD1184433caspase recruitment domain family, member 11
INFERRED
HumanGMNN51053geminin, DNA replication inhibitor
INFERRED
HumanFOXP350943forkhead box P3
img Jax MP, Pubmed Id: 19597499, MOUSE PHENOTYPE ID: MGI:2443552
img Jax MP, Pubmed Id: 18725525, MOUSE PHENOTYPE ID: MGI:2177178
img Jax MP, Pubmed Id: 20133615, MOUSE PHENOTYPE ID: MGI:1335098
img Jax MP, Pubmed Id: 22177923, MOUSE PHENOTYPE ID: MGI:2443256
img Jax MP, Pubmed Id: 18725527, MOUSE PHENOTYPE ID: MGI:1261425
img Jax MP, Pubmed Id: 22908322, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 20072126, MOUSE PHENOTYPE ID: MGI:1891436
HumanDROSHA29102drosha, ribonuclease type III
img Jax MP, Pubmed Id: 18725527, MOUSE PHENOTYPE ID: MGI:1261425
img Jax MP, Pubmed Id: 22177923, MOUSE PHENOTYPE ID: MGI:2443256
img Jax MP, Pubmed Id: 20072126, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 18725525, MOUSE PHENOTYPE ID: MGI:2177178
img Jax MP, Pubmed Id: 22908322, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 20133615, MOUSE PHENOTYPE ID: MGI:1335098
img Jax MP, Pubmed Id: 19597499, MOUSE PHENOTYPE ID: MGI:2443552
HumanLAT27040linker for activation of T cells
INFERRED
HumanDICER123405dicer 1, ribonuclease type III
img Jax MP, Pubmed Id: 20072126, MOUSE PHENOTYPE ID: MGI:1891436
img Jax MP, Pubmed Id: 19597499, MOUSE PHENOTYPE ID: MGI:2443552
img Jax MP, Pubmed Id: 20133615, MOUSE PHENOTYPE ID: MGI:1335098
img Jax MP, Pubmed Id: 22177923, MOUSE PHENOTYPE ID: MGI:2443256
img Jax MP, Pubmed Id: 18725525, MOUSE PHENOTYPE ID: MGI:2177178
img Jax MP, Pubmed Id: 18725527, MOUSE PHENOTYPE ID: MGI:1261425
img Jax MP, Pubmed Id: 22908322, MOUSE PHENOTYPE ID: MGI:1891436
HumanTXNIP10628thioredoxin interacting protein
INFERRED
HumanBATF10538basic leucine zipper transcription factor, ATF-like
INFERRED
HumanTESPA19840thymocyte expressed, positive selection associated 1
INFERRED
HumanTOX9760thymocyte selection-associated high mobility group box
INFERRED
HumanMAP3K149020mitogen-activated protein kinase kinase kinase 14
INFERRED
HumanIER38870immediate early response 3
INFERRED
HumanSOCS18651suppressor of cytokine signaling 1
INFERRED
HumanZAP707535zeta-chain (TCR) associated protein kinase 70kDa
INFERRED
HumanWAS7454Wiskott-Aldrich syndrome
INFERRED
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004941abnormal regulatory T cell morphology0self