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Details
Link-It Detail - Jax Mouse Phenotype - abnormal somatic hypermutation frequency
Debug Stats
  • ### Total Build Time: 49 ms 22.956 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 408 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 379 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 170 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=10 ms Completed: 10 ms rowSize= 1.024 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 10.985 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=31 ms Completed: 31 ms rowSize= 8.682 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.178 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal somatic hypermutation frequency MP:0004815
Definition (1)
any anomaly in the high frequency of programmed mutation that occurs in the gene segments encoding the variable regions of antibodies during the differentiation of individual B lymphocytes into antibody producing plasma cells
Synonyms (1)
"abnormal SHM" EXACT
Parents (2)
img abnormal adaptive immunity MP:0002420
img abnormal B cell differentiation MP:0002144
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal adaptive immunity MP:0002420
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img cellular phenotype MP:00053848img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal B cell differentiation MP:0002144
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal B cell differentiation MP:0002144
Genes (14)

Species:
human : 14
SpeciesGeneGeneIdGene NameEvidence
HumanFCAMR83953Fc receptor, IgA, IgM, high affinity
Click here to display 44 evidence detail records.
HumanBACH260468BTB and CNC homology 1, basic leucine zipper transcription factor 2
Click here to display 44 evidence detail records.
HumanAICDA57379activation-induced cytidine deaminase
Click here to display 44 evidence detail records.
HumanREV151455REV1, polymerase (DNA directed)
Click here to display 44 evidence detail records.
HumanPOLQ10721polymerase (DNA directed), theta
Click here to display 44 evidence detail records.
HumanUNG7374uracil-DNA glycosylase
Click here to display 44 evidence detail records.
HumanREV3L5980REV3-like, polymerase (DNA directed), zeta, catalytic subunit
Click here to display 44 evidence detail records.
HumanPKN15585protein kinase N1
Click here to display 44 evidence detail records.
HumanPCNA5111proliferating cell nuclear antigen
Click here to display 44 evidence detail records.
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
Click here to display 44 evidence detail records.
HumanIGBP13476immunoglobulin (CD79A) binding protein 1
Click here to display 44 evidence detail records.
HumanHOXC43221homeobox C4
Click here to display 44 evidence detail records.
HumanCD79A973CD79a molecule, immunoglobulin-associated alpha
Click here to display 44 evidence detail records.
HumanBCL6604B-cell CLL/lymphoma 6
Click here to display 44 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004815abnormal somatic hypermutation frequency0self