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Details
Link-It Detail - Jax Mouse Phenotype - decreased response of heart to induced stress
Debug Stats
  • ### Total Build Time: 49 ms 21.646 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 418 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 319 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 207 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.044 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 4.312 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=37 ms Completed: 37 ms rowSize= 14.032 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.183 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased response of heart to induced stress MP:0004486
Definition (1)
decrease in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding
Synonyms (1)
"increased protection of heart from induced stress" EXACT
Parents (2)
img altered response of heart to induced stress MP:0004484
img decreased susceptibility to injury MP:0005166
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img altered response of heart to induced stress MP:0004484
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053855img altered response of heart to induced stress MP:0004484
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img decreased susceptibility to injury MP:0005166
Genes (23)

Species:
human : 23
SpeciesGeneGeneIdGene NameEvidence
HumanNOX450507NADPH oxidase 4
Click here to display 38 evidence detail records.
HumanCAMTA223125calmodulin binding transcription activator 2
Click here to display 38 evidence detail records.
HumanRASSF111186Ras association (RalGDS/AF-6) domain family member 1
Click here to display 38 evidence detail records.
HumanMAP3K210746mitogen-activated protein kinase kinase kinase 2
Click here to display 38 evidence detail records.
HumanKDM4A9682lysine (K)-specific demethylase 4A
Click here to display 38 evidence detail records.
HumanCSRP38048cysteine and glycine-rich protein 3 (cardiac LIM protein)
Click here to display 38 evidence detail records.
HumanTLR47099toll-like receptor 4
Click here to display 38 evidence detail records.
HumanSLC9A16548solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
Click here to display 38 evidence detail records.
HumanPRKCA5578protein kinase C, alpha
Click here to display 38 evidence detail records.
HumanPPP3CB5532protein phosphatase 3, catalytic subunit, beta isozyme
Click here to display 38 evidence detail records.
HumanNFATC34775nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
Click here to display 38 evidence detail records.
HumanMAP3K54217mitogen-activated protein kinase kinase kinase 5
Click here to display 38 evidence detail records.
HumanMAOA4128monoamine oxidase A
Click here to display 38 evidence detail records.
HumanJUND3727jun D proto-oncogene
Click here to display 38 evidence detail records.
HumanGNA112767guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
Click here to display 38 evidence detail records.
HumanGATA42626GATA binding protein 4
Click here to display 38 evidence detail records.
HumanFHL12273four and a half LIM domains 1
Click here to display 38 evidence detail records.
HumanDUSP61848dual specificity phosphatase 6
Click here to display 38 evidence detail records.
HumanRCAN11827regulator of calcineurin 1
Click here to display 38 evidence detail records.
HumanCTNNB11499catenin (cadherin-associated protein), beta 1, 88kDa
Click here to display 38 evidence detail records.
HumanCAMK2D817calcium/calmodulin-dependent protein kinase II delta
Click here to display 38 evidence detail records.
HumanKLF5688Kruppel-like factor 5 (intestinal)
Click here to display 38 evidence detail records.
HumanAGTR2186angiotensin II receptor, type 2
Click here to display 38 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004486decreased response of heart to induced stress0self