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Details
Link-It Detail - Jax Mouse Phenotype - abnormal plasmacytoid dendritic cell morphology
Debug Stats
  • ### Total Build Time: 26 ms 15.257 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 422 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 528 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 170 bytes
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  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 600 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.283 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=16 ms Completed: 16 ms rowSize= 7.390 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.185 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal plasmacytoid dendritic cell morphology MP:0004242
Definition (1)
any structural anomaly of phagocytic dendritic cells that are morphologically similar to plasma cells, but do not express B lineage markers, and produce large amounts of alpha/beta interferons (IFN-/) in response to viral and bacterial stimuli; plasmacytoid dendritic cells are found in the thymic medulla and lymph node T cell areas and are responsible for immune tolerance
Synonyms (1)
"abnormal pDC" EXACT
Parents (1)
img abnormal dendritic cell morphology MP:0005461
Children (1)
img abnormal plasmacytoid dendritic cell number MP:0008123
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal dendritic cell morphology MP:0005461
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053977img abnormal dendritic cell morphology MP:0005461
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal dendritic cell morphology MP:0005461
Genes (12)

Species:
human : 12
SpeciesGeneGeneIdGene NameEvidence
HumanSPPL2A84888signal peptide peptidase like 2A
INFERRED
HumanTRAF3IP210758TRAF3 interacting protein 2
INFERRED
HumanSTAT26773signal transducer and activator of transcription 2, 113kDa
INFERRED
HumanPTPRC5788protein tyrosine phosphatase, receptor type, C
INFERRED
HumanNFKB24791nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
INFERRED
HumanIRF53663interferon regulatory factor 5
INFERRED
HumanIRF43662interferon regulatory factor 4
INFERRED
HumanIFNA133447interferon, alpha 13
img Jax MP, Pubmed Id: 17723216, MOUSE PHENOTYPE ID: MGI:107662
HumanIFNA13439interferon, alpha 1
img Jax MP, Pubmed Id: 17723216, MOUSE PHENOTYPE ID: MGI:107662
HumanFLT3LG2323fms-related tyrosine kinase 3 ligand
INFERRED
HumanFLT32322fms-related tyrosine kinase 3
INFERRED
HumanBCL3602B-cell CLL/lymphoma 3
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004242abnormal plasmacytoid dendritic cell morphology0self