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Details
Link-It Detail - Jax Mouse Phenotype - decreased cellular sensitivity to ionizing radiation
Debug Stats
  • ### Total Build Time: 28 ms 20.402 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 432 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 228 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 209 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 598 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.070 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 1.583 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=14 ms Completed: 14 ms rowSize= 14.982 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.189 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased cellular sensitivity to ionizing radiation MP:0004228
Definition (1)
decreased incidence of cell death following exposure to ionizing radiation
Synonyms (1)
"increased cellular resistance to ionizing radiation" EXACT
Parents (1)
img decreased sensitivity to induced cell death MP:0008944
Children (2)
img decreased cellular sensitivity to gamma-irradiation MP:0003207
img decreased cellular sensitivity to X-ray irradiation MP:0004587
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img decreased sensitivity to induced cell death MP:0008944
Genes (27)

Species:
human : 27
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPERP64065PERP, TP53 apoptosis effector
INFERRED
HumanCUL923113cullin 9
INFERRED
HumanCHEK211200checkpoint kinase 2
Click here to display 23 evidence detail records.
HumanNDRG110397N-myc downstream regulated 1
INFERRED
HumanPER28864period circadian clock 2
INFERRED
HumanTNFRSF10A8797tumor necrosis factor receptor superfamily, member 10a
INFERRED
HumanTP638626tumor protein p63
Click here to display 23 evidence detail records.
HumanTP737161tumor protein p73
INFERRED
HumanTP537157tumor protein p53
Click here to display 23 evidence detail records.
HumanRAD51D5892RAD51 paralog D
INFERRED
HumanPTPN65777protein tyrosine phosphatase, non-receptor type 6
INFERRED
HumanMAP2K65608mitogen-activated protein kinase kinase 6
INFERRED
HumanNIT14817nitrilase 1
INFERRED
HumanNBN4683nibrin
Click here to display 23 evidence detail records.
HumanMRE11A4361MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
Click here to display 23 evidence detail records.
HumanMEOX24223mesenchyme homeobox 2
Click here to display 23 evidence detail records.
HumanMDM44194Mdm4 p53 binding protein homolog (mouse)
INFERRED
HumanMDM24193MDM2 oncogene, E3 ubiquitin protein ligase
Click here to display 23 evidence detail records.
HumanHINT13094histidine triad nucleotide binding protein 1
INFERRED
HumanHELLS3070helicase, lymphoid-specific
INFERRED
HumanHIST1H1C3006histone cluster 1, H1c
INFERRED
HumanGPX12876glutathione peroxidase 1
INFERRED
HumanDDB21643damage-specific DNA binding protein 2, 48kDa
Click here to display 23 evidence detail records.
HumanCASP9842caspase 9, apoptosis-related cysteine peptidase
INFERRED
HumanBRCA2675breast cancer 2, early onset
Click here to display 23 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004228decreased cellular sensitivity to ionizing radiation0self