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Details
Link-It Detail - Jax Mouse Phenotype - abnormal cell cycle checkpoint function
Debug Stats
  • ### Total Build Time: 487 ms 21.658 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 406 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 368 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=25 ms Completed: 25 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=11 ms Completed: 11 ms rowSize= 574 bytes
  • CONCEPT_CHILDREN gt=11 ms Completed: 11 ms rowSize= 601 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.560 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=424 ms Completed: 424 ms rowSize= 16.874 KB
  • CONCEPT_XREFS gt=10 ms Completed: 10 ms rowSize= 1.177 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal cell cycle checkpoint function MP:0004045
Definition (1)
anomaly in the amount of time spent at the points in the cell cycle (end of G1 phase, end of G2 phase, and during metaphase) which prevent the cell from progressing to the next phase when conditions are unfavorable
Parents (1)
img abnormal cell cycle MP:0003077
Children (1)
img abnormal mitotic spindle assembly checkpoint MP:0009762
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053845img abnormal cell cycle MP:0003077
Genes (50)

Species:
human : 50
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SpeciesGeneGeneIdGene NameEvidence
HumanSETD8387893SET domain containing (lysine methyltransferase) 8
Click here to display 84 evidence detail records.
HumanSETD780854SET domain containing (lysine methyltransferase) 7
Click here to display 84 evidence detail records.
HumanTSPYL264061TSPY-like 2
Click here to display 84 evidence detail records.
HumanIFT12255764intraflagellar transport 122 homolog (Chlamydomonas)
Click here to display 84 evidence detail records.
HumanUIMC151720ubiquitin interaction motif containing 1
Click here to display 84 evidence detail records.
HumanCACYBP27101calcyclin binding protein
Click here to display 84 evidence detail records.
HumanSYF225949SYF2 pre-mRNA-splicing factor
Click here to display 84 evidence detail records.
HumanSIRT123411sirtuin 1
Click here to display 84 evidence detail records.
HumanSIN3B23309SIN3 transcription regulator family member B
Click here to display 84 evidence detail records.
HumanTPX222974TPX2, microtubule-associated
INFERRED
HumanCHEK211200checkpoint kinase 2
Click here to display 84 evidence detail records.
HumanCOPS510987COP9 signalosome subunit 5
Click here to display 84 evidence detail records.
HumanPSME310197proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
Click here to display 84 evidence detail records.
HumanRAD5010111RAD50 homolog (S. cerevisiae)
Click here to display 84 evidence detail records.
HumanPARP210038poly (ADP-ribose) polymerase 2
Click here to display 84 evidence detail records.
HumanMAFB9935v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
Click here to display 84 evidence detail records.
HumanPTTG19232pituitary tumor-transforming 1
Click here to display 84 evidence detail records.
HumanBUB39184BUB3 mitotic checkpoint protein
Click here to display 84 evidence detail records.
HumanMBD48930methyl-CpG binding domain protein 4
Click here to display 84 evidence detail records.
HumanCUL4A8451cullin 4A
Click here to display 84 evidence detail records.
HumanMAD1L18379MAD1 mitotic arrest deficient-like 1 (yeast)
INFERRED
HumanSMC1A8243structural maintenance of chromosomes 1A
Click here to display 84 evidence detail records.
HumanTP53BP27159tumor protein p53 binding protein, 2
Click here to display 84 evidence detail records.
HumanTP53BP17158tumor protein p53 binding protein 1
Click here to display 84 evidence detail records.
HumanTP537157tumor protein p53
Click here to display 84 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0004045abnormal cell cycle checkpoint function0self