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Details
Link-It Detail - Jax Mouse Phenotype - renal necrosis
Debug Stats
  • ### Total Build Time: 36 ms 82.726 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 356 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 227 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 173 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 574 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 579 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 1.571 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=29 ms Completed: 29 ms rowSize= 77.993 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
renal necrosis MP:0003946
Definition (1)
pathological cell death in the kidney, usually due to irreversible damage
Synonyms (1)
"kidney necrosis" EXACT
Parents (1)
img kidney degeneration MP:0009641
Children (1)
img renal tubular necrosis MP:0004154
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053676img kidney degeneration MP:0009641
Genes (25)

Species:
human : 25
SpeciesGeneGeneIdGene NameEvidence
HumanCRIM151232cysteine rich transmembrane BMP regulator 1 (chordin-like)
INFERRED
HumanRRM2B50484ribonucleotide reductase M2 B (TP53 inducible)
INFERRED
HumanTREX111277three prime repair exonuclease 1
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
HumanSLC7A911136solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
INFERRED
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
INFERRED
HumanTLR47099toll-like receptor 4
INFERRED
HumanTGFB17040transforming growth factor, beta 1
INFERRED
HumanSPTB6710spectrin, beta, erythrocytic
INFERRED
HumanSPTA16708spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
HumanSPP16696secreted phosphoprotein 1
INFERRED
HumanSALL16299sal-like 1 (Drosophila)
INFERRED
HumanPTGIS5740prostaglandin I2 (prostacyclin) synthase
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
HumanPKHD15314polycystic kidney and hepatic disease 1 (autosomal recessive)
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
INFERRED
HumanNOS14842nitric oxide synthase 1 (neuronal)
INFERRED
HumanMT1E4493metallothionein 1E
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
HumanSMAD34088SMAD family member 3
INFERRED
HumanITGB33690integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
HumanHMOX13162heme oxygenase (decycling) 1
INFERRED
HumanHELLS3070helicase, lymphoid-specific
INFERRED
HumanGSTZ12954glutathione S-transferase zeta 1
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
HumanDNASE11773deoxyribonuclease I
INFERRED
HumanCASP4837caspase 4, apoptosis-related cysteine peptidase
INFERRED
HumanBCR613breakpoint cluster region
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
HumanFAS355Fas cell surface death receptor
img Jax MP, Pubmed Id: 12052898, MOUSE PHENOTYPE ID: MGI:1341859
img Jax MP, Pubmed Id: 18212049, MOUSE PHENOTYPE ID: MGI:2182765
img Jax MP, Pubmed Id: 12403673, MOUSE PHENOTYPE ID: MGI:1097156
img Jax MP, Pubmed Id: 10966523, MOUSE PHENOTYPE ID: MGI:97171
img Jax MP, Pubmed Id: 11154235, MOUSE PHENOTYPE ID: MGI:98385
img Jax MP, Pubmed Id: 17142777, MOUSE PHENOTYPE ID: MGI:95484
img Jax MP, Pubmed Id: 18235088, MOUSE PHENOTYPE ID: MGI:2155808
img Jax MP, Pubmed Id: 7889565, MOUSE PHENOTYPE ID: MGI:88141
img Jax MP, Pubmed Id: 9916135, MOUSE PHENOTYPE ID: MGI:96612
img Jax MP, Pubmed Id: 15254239, MOUSE PHENOTYPE ID: MGI:1328317
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0003946renal necrosis0self