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Details
Link-It Detail - Jax Mouse Phenotype - impaired granulosa cell differentiation
Debug Stats
  • ### Total Build Time: 86 ms 80.502 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 406 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 476 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=11 ms Completed: 11 ms rowSize= 1.030 KB
  • CONCEPT_CHILDREN gt=11 ms Completed: 11 ms rowSize= 582 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=18 ms Completed: 18 ms rowSize= 5.628 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=37 ms Completed: 37 ms rowSize= 71.093 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.177 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
impaired granulosa cell differentiation MP:0003357
Definition (1)
atypical production of or inability to produce the supporting cells for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle
Parents (2)
img abnormal cell differentiation MP:0005076
img abnormal granulosa cell morphology MP:0008868
Children (1)
img abnormal cumulus oophorus MP:0009372
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053845img abnormal cell differentiation MP:0005076
img mammalian phenotype MP:0000001img reproductive system phenotype MP:000538910img abnormal granulosa cell morphology MP:0008868
img mammalian phenotype MP:0000001img endocrine/exocrine gland phenotype MP:00053798img abnormal granulosa cell morphology MP:0008868
img mammalian phenotype MP:0000001img reproductive system phenotype MP:00053898img abnormal granulosa cell morphology MP:0008868
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanSOHLH254937spermatogenesis and oogenesis specific basic helix-loop-helix 2
img Jax MP, Pubmed Id: 18339713, MOUSE PHENOTYPE ID: MGI:1352467
img Jax MP, Pubmed Id: 15013804, MOUSE PHENOTYPE ID: MGI:97384
img Jax MP, Pubmed Id: 10342859, MOUSE PHENOTYPE ID: MGI:97798
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 9303532, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 8788202, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:3799680
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 18606860, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 18753606, MOUSE PHENOTYPE ID: MGI:1921684
HumanZP37784zona pellucida glycoprotein 3 (sperm receptor)
INFERRED
HumanZP27783zona pellucida glycoprotein 2 (sperm receptor)
INFERRED
HumanPTX35806pentraxin 3, long
INFERRED
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img Jax MP, Pubmed Id: 9303532, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 18753606, MOUSE PHENOTYPE ID: MGI:1921684
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:3799680
img Jax MP, Pubmed Id: 18339713, MOUSE PHENOTYPE ID: MGI:1352467
img Jax MP, Pubmed Id: 15013804, MOUSE PHENOTYPE ID: MGI:97384
img Jax MP, Pubmed Id: 18606860, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 8788202, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 10342859, MOUSE PHENOTYPE ID: MGI:97798
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
HumanPTEN5728phosphatase and tensin homolog
img Jax MP, Pubmed Id: 9303532, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 10342859, MOUSE PHENOTYPE ID: MGI:97798
img Jax MP, Pubmed Id: 8788202, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 15013804, MOUSE PHENOTYPE ID: MGI:97384
img Jax MP, Pubmed Id: 18339713, MOUSE PHENOTYPE ID: MGI:1352467
img Jax MP, Pubmed Id: 18753606, MOUSE PHENOTYPE ID: MGI:1921684
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 18606860, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:3799680
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:109583
HumanNTRK24915neurotrophic tyrosine kinase, receptor, type 2
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 8788202, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 18339713, MOUSE PHENOTYPE ID: MGI:1352467
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 18753606, MOUSE PHENOTYPE ID: MGI:1921684
img Jax MP, Pubmed Id: 9303532, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:3799680
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 18606860, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 15013804, MOUSE PHENOTYPE ID: MGI:97384
img Jax MP, Pubmed Id: 10342859, MOUSE PHENOTYPE ID: MGI:97798
HumanESR22100estrogen receptor 2 (ER beta)
img Jax MP, Pubmed Id: 9303532, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 18606860, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:3799680
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 15013804, MOUSE PHENOTYPE ID: MGI:97384
img Jax MP, Pubmed Id: 18753606, MOUSE PHENOTYPE ID: MGI:1921684
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 8788202, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 18339713, MOUSE PHENOTYPE ID: MGI:1352467
img Jax MP, Pubmed Id: 10342859, MOUSE PHENOTYPE ID: MGI:97798
HumanESR12099estrogen receptor 1
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 18339713, MOUSE PHENOTYPE ID: MGI:1352467
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:3799680
img Jax MP, Pubmed Id: 9303532, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 15013804, MOUSE PHENOTYPE ID: MGI:97384
img Jax MP, Pubmed Id: 18753606, MOUSE PHENOTYPE ID: MGI:1921684
img Jax MP, Pubmed Id: 18606860, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 10342859, MOUSE PHENOTYPE ID: MGI:97798
img Jax MP, Pubmed Id: 8788202, MOUSE PHENOTYPE ID: MGI:1339753
HumanCSF11435colony stimulating factor 1 (macrophage)
img Jax MP, Pubmed Id: 18753606, MOUSE PHENOTYPE ID: MGI:1921684
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 15013804, MOUSE PHENOTYPE ID: MGI:97384
img Jax MP, Pubmed Id: 18606860, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 10342859, MOUSE PHENOTYPE ID: MGI:97798
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:3799680
img Jax MP, Pubmed Id: 8788202, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 18339713, MOUSE PHENOTYPE ID: MGI:1352467
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 9303532, MOUSE PHENOTYPE ID: MGI:88373
HumanCEBPB1051CCAAT/enhancer binding protein (C/EBP), beta
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 21860425, MOUSE PHENOTYPE ID: MGI:3799680
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 18753606, MOUSE PHENOTYPE ID: MGI:1921684
img Jax MP, Pubmed Id: 9303532, MOUSE PHENOTYPE ID: MGI:88373
img Jax MP, Pubmed Id: 18339713, MOUSE PHENOTYPE ID: MGI:1352467
img Jax MP, Pubmed Id: 10342859, MOUSE PHENOTYPE ID: MGI:97798
img Jax MP, Pubmed Id: 8788202, MOUSE PHENOTYPE ID: MGI:1339753
img Jax MP, Pubmed Id: 10976058, MOUSE PHENOTYPE ID: MGI:109392
img Jax MP, Pubmed Id: 18606860, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 15013804, MOUSE PHENOTYPE ID: MGI:97384
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0003357impaired granulosa cell differentiation0self