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Details
Link-It Detail - Jax Mouse Phenotype - loss of dopaminergic neurons
Debug Stats
  • ### Total Build Time: 37 ms 12.259 KB
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Jax Mouse Phenotype (1)
loss of dopaminergic neurons MP:0003244
Definition (1)
loss of the neurons that utilize dopamine as a neurotransmitter, commonly due to an apoptotic event
Parents (1)
img abnormal dopaminergic neuron morphology MP:0003243
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036316img abnormal dopaminergic neuron morphology MP:0003243
Genes (13)

Species:
human : 13
SpeciesGeneGeneIdGene NameEvidence
HumanTGFB37043transforming growth factor, beta 3
Click here to display 33 evidence detail records.
HumanTFAM7019transcription factor A, mitochondrial
Click here to display 33 evidence detail records.
HumanSNCA6622synuclein, alpha (non A4 component of amyloid precursor)
Click here to display 33 evidence detail records.
HumanSLC6A36531solute carrier family 6 (neurotransmitter transporter), member 3
Click here to display 33 evidence detail records.
HumanSDHD6392succinate dehydrogenase complex, subunit D, integral membrane protein
Click here to display 33 evidence detail records.
HumanPITX35309paired-like homeodomain 3
Click here to display 33 evidence detail records.
HumanPARK25071parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Click here to display 33 evidence detail records.
HumanOTX25015orthodenticle homeobox 2
Click here to display 33 evidence detail records.
HumanNR4A24929nuclear receptor subfamily 4, group A, member 2
Click here to display 33 evidence detail records.
HumanID23398inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Click here to display 33 evidence detail records.
HumanGRN2896granulin
Click here to display 33 evidence detail records.
HumanGFRA12674GDNF family receptor alpha 1
Click here to display 33 evidence detail records.
HumanEN12019engrailed homeobox 1
Click here to display 33 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0003244loss of dopaminergic neurons0self