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Details
Link-It Detail - Jax Mouse Phenotype - increased cardiomyocyte apoptosis
Debug Stats
  • ### Total Build Time: 277 ms 25.874 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 233 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.019 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 5.585 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=257 ms Completed: 257 ms rowSize= 17.335 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.171 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased cardiomyocyte apoptosis MP:0003222
Definition (1)
increase in the number of cardiac muscle cells undergoing programmed cell death
Parents (2)
img abnormal cardiomyocyte apoptosis MP:0003221
img increased apoptosis MP:0006042
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img muscle phenotype MP:00053695img abnormal cardiomyocyte apoptosis MP:0003221
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053856img abnormal cardiomyocyte apoptosis MP:0003221
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal cardiomyocyte apoptosis MP:0003221
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img increased apoptosis MP:0006042
Genes (43)

Species:
human : 43
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Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanXIRP2129446xin actin-binding repeat containing 2
Click here to display 68 evidence detail records.
HumanDOT1L84444DOT1-like histone H3K79 methyltransferase
Click here to display 68 evidence detail records.
HumanTRIM5457159tripartite motif containing 54
Click here to display 68 evidence detail records.
HumanSIRT751547sirtuin 7
Click here to display 68 evidence detail records.
HumanZFPM223414zinc finger protein, FOG family member 2
Click here to display 68 evidence detail records.
HumanKIFAP322920kinesin-associated protein 3
Click here to display 68 evidence detail records.
HumanINPP5F22876inositol polyphosphate-5-phosphatase F
Click here to display 68 evidence detail records.
HumanYWHAQ10971tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Click here to display 68 evidence detail records.
HumanIVNS1ABP10625influenza virus NS1A binding protein
Click here to display 68 evidence detail records.
HumanUBE4B10277ubiquitination factor E4B
Click here to display 68 evidence detail records.
HumanCALCRL10203calcitonin receptor-like
Click here to display 68 evidence detail records.
HumanBAG39531BCL2-associated athanogene 3
Click here to display 68 evidence detail records.
HumanAIFM19131apoptosis-inducing factor, mitochondrion-associated, 1
Click here to display 68 evidence detail records.
HumanDNAJA39093DnaJ (Hsp40) homolog, subfamily A, member 3
Click here to display 68 evidence detail records.
HumanNOL38996nucleolar protein 3 (apoptosis repressor with CARD domain)
Click here to display 68 evidence detail records.
HumanTCAP8557titin-cap
Click here to display 68 evidence detail records.
HumanTFAM7019transcription factor A, mitochondrial
Click here to display 68 evidence detail records.
HumanSTAT36774signal transducer and activator of transcription 3 (acute-phase response factor)
Click here to display 68 evidence detail records.
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
Click here to display 68 evidence detail records.
HumanSRF6722serum response factor (c-fos serum response element-binding transcription factor)
Click here to display 68 evidence detail records.
HumanSOS16654son of sevenless homolog 1 (Drosophila)
Click here to display 68 evidence detail records.
HumanSOD26648superoxide dismutase 2, mitochondrial
Click here to display 68 evidence detail records.
HumanSLC8A16546solute carrier family 8 (sodium/calcium exchanger), member 1
Click here to display 68 evidence detail records.
HumanRASA15921RAS p21 protein activator (GTPase activating protein) 1
Click here to display 68 evidence detail records.
HumanMAPK85599mitogen-activated protein kinase 8
Click here to display 68 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0003222increased cardiomyocyte apoptosis0self