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Details
Link-It Detail - Jax Mouse Phenotype - increased susceptibility to ischemic brain injury
Debug Stats
  • ### Total Build Time: 32 ms 23.992 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 426 bytes
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  • CONCEPT_GENES gt=30 ms Completed: 30 ms rowSize= 15.764 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.187 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
increased susceptibility to ischemic brain injury MP:0003076
Definition (1)
increased frequency or more severe response, such as necrotic tissue size, to lack of adequate blood flow, due to trauma or disease, to support the normal functioning of all or part of the brain tissue, compared to controls
Synonyms (1)
"decreased resistance to ischemic brain injury" EXACT
Parents (2)
img increased susceptibility to injury MP:0005165
img altered response to CNS ischemic injury MP:0003075
Children (1)
img increased cerebral infarction size MP:0006060
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img increased susceptibility to injury MP:0005165
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036315img altered response to CNS ischemic injury MP:0003075
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053765img altered response to CNS ischemic injury MP:0003075
Genes (29)

Species:
human : 29
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanITPRIP85450inositol 1,4,5-trisphosphate receptor interacting protein
INFERRED
HumanNDFIP180762Nedd4 family interacting protein 1
INFERRED
HumanNDRG465009NDRG family member 4
Click here to display 27 evidence detail records.
HumanNEIL355247nei endonuclease VIII-like 3 (E. coli)
INFERRED
HumanFAIM223017Fas apoptotic inhibitory molecule 2
INFERRED
HumanHYOU110525hypoxia up-regulated 1
Click here to display 27 evidence detail records.
HumanUNG7374uracil-DNA glycosylase
Click here to display 27 evidence detail records.
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
INFERRED
HumanTMBIM67009transmembrane BAX inhibitor motif containing 6
Click here to display 27 evidence detail records.
HumanSLC8A36547solute carrier family 8 (sodium/calcium exchanger), member 3
INFERRED
HumanRASGRF25924Ras protein-specific guanine nucleotide-releasing factor 2
Click here to display 27 evidence detail records.
HumanPTGER25732prostaglandin E receptor 2 (subtype EP2), 53kDa
INFERRED
HumanPSPN5623persephin
Click here to display 27 evidence detail records.
HumanNOTCH34854notch 3
Click here to display 27 evidence detail records.
HumanNFE2L24780nuclear factor, erythroid 2-like 2
Click here to display 27 evidence detail records.
HumanKCNK23776potassium channel, subfamily K, member 2
Click here to display 27 evidence detail records.
HumanIL103586interleukin 10
INFERRED
HumanHIF1A3091hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Click here to display 27 evidence detail records.
HumanGSN2934gelsolin
Click here to display 27 evidence detail records.
HumanGPX12876glutathione peroxidase 1
Click here to display 27 evidence detail records.
HumanF2RL12150coagulation factor II (thrombin) receptor-like 1
INFERRED
HumanCST31471cystatin C
INFERRED
HumanCNTF1270ciliary neurotrophic factor
INFERRED
HumanCNR11268cannabinoid receptor 1 (brain)
Click here to display 27 evidence detail records.
HumanENTPD1953ectonucleoside triphosphate diphosphohydrolase 1
Click here to display 27 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0003076increased susceptibility to ischemic brain injury0self