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Details
Link-It Detail - Jax Mouse Phenotype - abnormal paired-pulse facilitation
Debug Stats
  • ### Total Build Time: 28 ms 29.418 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 170 bytes
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  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=19 ms Completed: 19 ms rowSize= 24.002 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal paired-pulse facilitation MP:0002918
Definition (1)
defects in the enhanced response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to lack of increase of neurotransmitter release at the second stimulus
Synonyms (1)
"abnormal PPF" EXACT
Parents (1)
img abnormal synaptic transmission MP:0003635
Children (2)
img decreased paired-pulse facilitation MP:0002920
img enhanced paired-pulse facilitation MP:0002919
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036315img abnormal synaptic transmission MP:0003635
Genes (45)

Species:
human : 45
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanUNC13C440279unc-13 homolog C (C. elegans)
INFERRED
HumanSPRED1161742sprouty-related, EVH1 domain containing 1
INFERRED
HumanSTXBP5134957syntaxin binding protein 5 (tomosyn)
INFERRED
HumanSYT2127833synaptotagmin II
INFERRED
HumanRAB3C115827RAB3C, member RAS oncogene family
INFERRED
HumanFOXP293986forkhead box P2
INFERRED
HumanCADPS293664Ca++-dependent secretion activator 2
img Jax MP, Pubmed Id: 12152079, MOUSE PHENOTYPE ID: MGI:104615
img Jax MP, Pubmed Id: 19039037, MOUSE PHENOTYPE ID: MGI:3834567
img Jax MP, Pubmed Id: 9581771, MOUSE PHENOTYPE ID: MGI:96654
img Jax MP, Pubmed Id: 17344385, MOUSE PHENOTYPE ID: MGI:2443963
img Jax MP, Pubmed Id: 16914668, MOUSE PHENOTYPE ID: MGI:2181421
img Jax MP, Pubmed Id: 19701204, MOUSE PHENOTYPE ID: MGI:5306986
img Jax MP, Pubmed Id: 11797009, MOUSE PHENOTYPE ID: MGI:2152971
HumanSTON285439stonin 2
INFERRED
HumanFBXL2084961F-box and leucine-rich repeat protein 20
INFERRED
HumanEHMT179813euchromatic histone-lysine N-methyltransferase 1
INFERRED
HumanLYNX166004Ly6/neurotoxin 1
INFERRED
HumanFGF2227006fibroblast growth factor 22
INFERRED
HumanBACE123621beta-site APP-cleaving enzyme 1
INFERRED
HumanTNIK23043TRAF2 and NCK interacting kinase
INFERRED
HumanRIMS122999regulating synaptic membrane exocytosis 1
img Jax MP, Pubmed Id: 9581771, MOUSE PHENOTYPE ID: MGI:96654
img Jax MP, Pubmed Id: 19701204, MOUSE PHENOTYPE ID: MGI:5306986
img Jax MP, Pubmed Id: 16914668, MOUSE PHENOTYPE ID: MGI:2181421
img Jax MP, Pubmed Id: 17344385, MOUSE PHENOTYPE ID: MGI:2443963
img Jax MP, Pubmed Id: 19039037, MOUSE PHENOTYPE ID: MGI:3834567
img Jax MP, Pubmed Id: 12152079, MOUSE PHENOTYPE ID: MGI:104615
img Jax MP, Pubmed Id: 11797009, MOUSE PHENOTYPE ID: MGI:2152971
HumanRAB3GAP122930RAB3 GTPase activating protein subunit 1 (catalytic)
INFERRED
HumanCSPG510675chondroitin sulfate proteoglycan 5 (neuroglycan C)
INFERRED
HumanSNPH9751syntaphilin
INFERRED
HumanSYNGR19145synaptogyrin 1
INFERRED
HumanCHRD8646chordin
INFERRED
HumanVDAC37419voltage-dependent anion channel 3
INFERRED
HumanVDAC17416voltage-dependent anion channel 1
INFERRED
HumanUCHL17345ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
INFERRED
HumanSYN16853synapsin I
INFERRED
HumanSNAP256616synaptosomal-associated protein, 25kDa
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002918abnormal paired-pulse facilitation0self