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Details
Link-It Detail - Jax Mouse Phenotype - increased circulating aldosterone level
Debug Stats
  • ### Total Build Time: 90 ms 22.158 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 406 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 329 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 195 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 1.050 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=18 ms Completed: 18 ms rowSize= 7.037 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=57 ms Completed: 57 ms rowSize= 11.834 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.177 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased circulating aldosterone level MP:0002666
Definition (1)
increased in the blood concentration of the hormone that is secreted by the adrenal cortex and regulates sodium conservation and potassium secretion in the distal renal tubule
Synonyms (1)
"elevated serum levels of aldosterone" NARROW
Parents (2)
img abnormal circulating aldosterone level MP:0005346
img increased circulating mineralocorticoid level MP:0003373
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating aldosterone level MP:0005346
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating aldosterone level MP:0005346
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal circulating aldosterone level MP:0005346
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img increased circulating mineralocorticoid level MP:0003373
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img increased circulating mineralocorticoid level MP:0003373
Genes (19)

Species:
human : 19
SpeciesGeneGeneIdGene NameEvidence
HumanSTK3927347serine threonine kinase 39
Click here to display 27 evidence detail records.
HumanDKK327122dickkopf WNT signaling pathway inhibitor 3
Click here to display 27 evidence detail records.
HumanNEDD4L23327neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Click here to display 27 evidence detail records.
HumanVAV310451vav 3 guanine nucleotide exchange factor
Click here to display 27 evidence detail records.
HumanSLC4A48671solute carrier family 4 (sodium bicarbonate cotransporter), member 4
Click here to display 27 evidence detail records.
HumanBSND7809Bartter syndrome, infantile, with sensorineural deafness (Barttin)
Click here to display 27 evidence detail records.
HumanVAV27410vav 2 guanine nucleotide exchange factor
Click here to display 27 evidence detail records.
HumanTGFB17040transforming growth factor, beta 1
Click here to display 27 evidence detail records.
HumanSLC9A36550solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Click here to display 27 evidence detail records.
HumanSGK16446serum/glucocorticoid regulated kinase 1
Click here to display 27 evidence detail records.
HumanSCNN1B6338sodium channel, non-voltage-gated 1, beta subunit
Click here to display 27 evidence detail records.
HumanREN5972renin
Click here to display 27 evidence detail records.
HumanPCMT15110protein-L-isoaspartate (D-aspartate) O-methyltransferase
Click here to display 27 evidence detail records.
HumanNR3C24306nuclear receptor subfamily 3, group C, member 2
Click here to display 27 evidence detail records.
HumanKCNK33777potassium channel, subfamily K, member 3
Click here to display 27 evidence detail records.
HumanKCNE13753potassium voltage-gated channel, Isk-related family, member 1
Click here to display 27 evidence detail records.
HumanNR3C12908nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Click here to display 27 evidence detail records.
HumanSLC26A31811solute carrier family 26 (anion exchanger), member 3
Click here to display 27 evidence detail records.
HumanCLDN71366claudin 7
Click here to display 27 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002666increased circulating aldosterone level0self