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Details
Link-It Detail - Jax Mouse Phenotype - abnormal type III hypersensitivity reaction
Debug Stats
  • ### Total Build Time: 19 ms 13.473 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 414 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 441 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 198 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=5 ms Completed: 5 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.481 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.092 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.255 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 4.291 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal type III hypersensitivity reaction MP:0002533
Definition (1)
anomaly in the tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via Abs encountering circulating Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury
Synonyms (1)
"immune complex mediated hypersensitivity" EXACT
Parents (3)
img abnormal adaptive immunity MP:0002420
img abnormal hypersensitivity reaction MP:0002148
img abnormal acute inflammation MP:0002498
Children (2)
img decreased susceptibility to type III hypersensitivity reaction MP:0005614
img increased susceptibility to type III hypersensitivity reaction MP:0005615
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal adaptive immunity MP:0002420
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal hypersensitivity reaction MP:0002148
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal acute inflammation MP:0002498
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanCCL3L3414062chemokine (C-C motif) ligand 3-like 3
INFERRED
HumanIKZF322806IKAROS family zinc finger 3 (Aiolos)
img Jax MP
img Jax MP, Pubmed Id: 12574333, MOUSE PHENOTYPE ID: MGI:1342542
HumanCCL3L16349chemokine (C-C motif) ligand 3-like 1
INFERRED
HumanCFH3075complement factor H
INFERRED
HumanCCR11230chemokine (C-C motif) receptor 1
INFERRED
HumanFAS355Fas cell surface death receptor
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002533abnormal type III hypersensitivity reaction0self