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Details
Link-It Detail - Jax Mouse Phenotype - abnormal type II hypersensitivity reaction
Debug Stats
  • ### Total Build Time: 31 ms 10.564 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 412 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 384 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 193 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 1.481 KB
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 1.090 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.255 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 1.448 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.180 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal type II hypersensitivity reaction MP:0002532
Definition (1)
anomaly in the response caused by an Ag-Ab reaction; antibodies are directly or indirectly cytotoxic to antigens on cell surfaces or in connective tissues; most often involves IgG and IgM; complement activation is usually involved
Synonyms (1)
"antibody-mediated cellular toxicity" EXACT
Parents (3)
img abnormal hypersensitivity reaction MP:0002148
img abnormal acute inflammation MP:0002498
img abnormal adaptive immunity MP:0002420
Children (2)
img increased susceptibility to type II hypersensitivity reaction MP:0005613
img decreased susceptibility to type II hypersensitivity reaction MP:0005612
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal hypersensitivity reaction MP:0002148
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal acute inflammation MP:0002498
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal adaptive immunity MP:0002420
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanFCGR2A2212Fc fragment of IgG, low affinity IIa, receptor (CD32)
INFERRED
HumanCD40958CD40 molecule, TNF receptor superfamily member 5
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002532abnormal type II hypersensitivity reaction0self