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Details
Link-It Detail - Jax Mouse Phenotype - abnormal type I hypersensitivity reaction
Debug Stats
  • ### Total Build Time: 66 ms 23.706 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 417 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 169 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 1.481 KB
  • CONCEPT_CHILDREN gt=6 ms Completed: 6 ms rowSize= 1.088 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 4.255 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=37 ms Completed: 37 ms rowSize= 14.586 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal type I hypersensitivity reaction MP:0002531
Definition (1)
anomaly in a reaction manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Synonyms (1)
"anaphylaxis" EXACT
Parents (3)
img abnormal adaptive immunity MP:0002420
img abnormal hypersensitivity reaction MP:0002148
img abnormal acute inflammation MP:0002498
Children (2)
img increased susceptibility to type I hypersensitivity reaction MP:0005596
img decreased susceptibility to type I hypersensitivity reaction MP:0005597
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal adaptive immunity MP:0002420
img mammalian phenotype MP:0000001img immune system phenotype MP:00053875img abnormal hypersensitivity reaction MP:0002148
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal acute inflammation MP:0002498
Genes (55)

Species:
human : 55
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanCD300LF146722CD300 molecule-like family member f
INFERRED
HumanORAI184876ORAI calcium release-activated calcium modulator 1
INFERRED
HumanIL2564806interleukin 25
INFERRED
HumanCYSLTR257105cysteinyl leukotriene receptor 2
INFERRED
HumanTRPM454795transient receptor potential cation channel, subfamily M, member 4
INFERRED
HumanDUSP1011221dual specificity phosphatase 10
INFERRED
HumanCORO1A11151coronin, actin binding protein, 1A
INFERRED
HumanCYSLTR110800cysteinyl leukotriene receptor 1
INFERRED
HumanGAB29846GRB2-associated binding protein 2
INFERRED
HumanLPAR29170lysophosphatidic acid receptor 2
INFERRED
HumanCCRL29034chemokine (C-C motif) receptor-like 2
INFERRED
HumanVAMP88673vesicle-associated membrane protein 8
Click here to display 9 evidence detail records.
HumanPIP5K1B8395phosphatidylinositol-4-phosphate 5-kinase, type I, beta
INFERRED
HumanVIPR27434vasoactive intestinal peptide receptor 2
INFERRED
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
INFERRED
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
INFERRED
HumanTBXA2R6915thromboxane A2 receptor
Click here to display 9 evidence detail records.
HumanSUV39H16839suppressor of variegation 3-9 homolog 1 (Drosophila)
INFERRED
HumanSTXBP26813syntaxin binding protein 2
INFERRED
HumanSTIM16786stromal interaction molecule 1
INFERRED
HumanSERPINB46318serpin peptidase inhibitor, clade B (ovalbumin), member 4
INFERRED
HumanRGS136003regulator of G-protein signaling 13
INFERRED
HumanPTPRC5788protein tyrosine phosphatase, receptor type, C
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002531abnormal type I hypersensitivity reaction0self