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Details
Link-It Detail - Jax Mouse Phenotype - abnormal macrophage morphology
Debug Stats
  • ### Total Build Time: 129 ms 33.076 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 388 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 432 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 193 bytes
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  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 1.063 KB
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  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 8.382 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=106 ms Completed: 106 ms rowSize= 15.634 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.168 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal macrophage morphology MP:0002446
Definition (1)
any structural anomaly of the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells
Synonyms (1)
"mononuclear phagocyte abnormalities" BROAD
Parents (2)
img abnormal professional antigen presenting cell morphology MP:0008195
img abnormal mononuclear phagocyte morphology MP:0008248
Children (12)
img abnormal alveolar macrophage morphology MP:0008245
img abnormal macrophage differentiation MP:0008113
img abnormal metallophilic macrophage morphology MP:0008241
img decreased macrophage cell number MP:0003884
img abnormal spleen marginal zone macrophage morphology MP:0008240
img abnormal microglial cell morphology MP:0000136
img abnormal osteoclast morphology MP:0004982
img abnormal perivascular macrophage morphology MP:0008242
img increased macrophage cell number MP:0005425
img abnormal peritoneal macrophage morphology MP:0008244
img abnormal Kupffer cell morphology MP:0008114
img abnormal macrophage derived foam cell morphology MP:0008243
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal professional antigen presenting cell morphology MP:0008195
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal mononuclear phagocyte morphology MP:0008248
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal mononuclear phagocyte morphology MP:0008248
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal mononuclear phagocyte morphology MP:0008248
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal mononuclear phagocyte morphology MP:0008248
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal mononuclear phagocyte morphology MP:0008248
Genes (319)

Species:
human : 319
Page Size
Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
INFERRED
HumanSUMF1285362sulfatase modifying factor 1
Click here to display 43 evidence detail records.
HumanSIGLEC15284266sialic acid binding Ig-like lectin 15
INFERRED
HumanATP6V0D2245972ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
INFERRED
HumanGPR116221395G protein-coupled receptor 116
INFERRED
HumanGJD4219770gap junction protein, delta 4, 40.1kDa
INFERRED
HumanB3GNT6192134UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
INFERRED
HumanTMEM64169200transmembrane protein 64
INFERRED
HumanSGMS2166929sphingomyelin synthase 2
Click here to display 43 evidence detail records.
HumanNKX2-3159296
INFERRED
HumanHFE2148738hemochromatosis type 2 (juvenile)
Click here to display 43 evidence detail records.
HumanCCBE1147372collagen and calcium binding EGF domains 1
INFERRED
HumanIL34146433interleukin 34
INFERRED
HumanPPARGC1B133522peroxisome proliferator-activated receptor gamma, coactivator 1 beta
INFERRED
HumanOSCAR126014osteoclast associated, immunoglobulin-like receptor
INFERRED
HumanMSI2124540musashi RNA-binding protein 2
INFERRED
HumanJDP2122953Jun dimerization protein 2
INFERRED
HumanSPIC121599Spi-C transcription factor (Spi-1/PU.1 related)
Click here to display 43 evidence detail records.
HumanLRRK2120892leucine-rich repeat kinase 2
INFERRED
HumanTWIST2117581twist basic helix-loop-helix transcription factor 2
INFERRED
HumanNXNL1115861nucleoredoxin-like 1
INFERRED
HumanITCH83737itchy E3 ubiquitin protein ligase
INFERRED
HumanDCSTAMP81501dendrocyte expressed seven transmembrane protein
INFERRED
HumanDOK379930docking protein 3
INFERRED
HumanSTEAP479689STEAP family member 4
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002446abnormal macrophage morphology0self