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Details
Link-It Detail - Jax Mouse Phenotype - abnormal spleen germinal center morphology
Debug Stats
  • ### Total Build Time: 164 ms 24.375 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 412 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 321 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 602 bytes
  • CONCEPT_CHILDREN gt=9 ms Completed: 9 ms rowSize= 2.430 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=10 ms Completed: 10 ms rowSize= 2.956 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=126 ms Completed: 126 ms rowSize= 16.179 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.180 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal spleen germinal center morphology MP:0002359
Definition (1)
any structural anomaly of the area of the spleen secondary B follicle where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs
Synonyms (1)
"abnormal spleen GC morphology" EXACT
Parents (1)
img abnormal spleen secondary B follicle morphology MP:0008472
Children (5)
img absent spleen germinal center MP:0008474
img increased spleen germinal center number MP:0008481
img decreased spleen germinal center number MP:0008482
img increased spleen germinal center size MP:0008483
img decreased spleen germinal center size MP:0008484
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal spleen secondary B follicle morphology MP:0008472
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053978img abnormal spleen secondary B follicle morphology MP:0008472
Genes (101)

Species:
human : 101
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGABPB2126626GA binding protein transcription factor, beta subunit 2
INFERRED
HumanABCC1089845ATP-binding cassette, sub-family C (CFTR/MRP), member 10
INFERRED
HumanB3GNT584002UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Click here to display 39 evidence detail records.
HumanFCAMR83953Fc receptor, IgA, IgM, high affinity
Click here to display 39 evidence detail records.
HumanSHARPIN81858SHANK-associated RH domain interactor
INFERRED
HumanDOCK881704dedicator of cytokinesis 8
INFERRED
HumanIL2159067interleukin 21
Click here to display 39 evidence detail records.
HumanBANK155024B-cell scaffold protein with ankyrin repeats 1
Click here to display 39 evidence detail records.
HumanPPP2R3C55012protein phosphatase 2, regulatory subunit B'', gamma
INFERRED
HumanLAX154900lymphocyte transmembrane adaptor 1
Click here to display 39 evidence detail records.
HumanDEF650619differentially expressed in FDCP 6 homolog (mouse)
Click here to display 39 evidence detail records.
HumanICOS29851inducible T-cell co-stimulator
Click here to display 39 evidence detail records.
HumanTNFRSF2127242tumor necrosis factor receptor superfamily, member 21
INFERRED
HumanLAT27040linker for activation of T cells
INFERRED
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
INFERRED
HumanTNFRSF13B23495tumor necrosis factor receptor superfamily, member 13B
INFERRED
HumanICOSLG23308inducible T-cell co-stimulator ligand
Click here to display 39 evidence detail records.
HumanIKZF322806IKAROS family zinc finger 3 (Aiolos)
INFERRED
HumanTRAF3IP210758TRAF3 interacting protein 2
INFERRED
HumanCXCL1310563chemokine (C-X-C motif) ligand 13
INFERRED
HumanSEMA4D10507sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
INFERRED
HumanIKZF110320IKAROS family zinc finger 1 (Ikaros)
INFERRED
HumanTNIP110318TNFAIP3 interacting protein 1
Click here to display 39 evidence detail records.
HumanTCIRG110312T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
INFERRED
HumanTRIP109322thyroid hormone receptor interactor 10
Click here to display 39 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0002359abnormal spleen germinal center morphology0self