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Details
Link-It Detail - Jax Mouse Phenotype - abnormal antigen presentation
Debug Stats
  • ### Total Build Time: 27 ms 22.317 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 386 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_GENES gt=21 ms Completed: 21 ms rowSize= 15.029 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.167 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal antigen presentation MP:0001835
Definition (1)
aberration in the process by which by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex
Synonyms (1)
"antigen presentation dysfunction" EXACT
Parents (1)
img abnormal immune system physiology MP:0001790
Children (6)
img abnormal B lymphocyte antigen presentation MP:0002453
img abnormal macrophage antigen presentation MP:0002454
img abnormal dendritic cell antigen presentation MP:0002455
img abnormal follicular dendritic cell antigen presentation MP:0008198
img abnormal antigen presentation via MHC class I MP:0001836
img abnormal antigen presentation via MHC class II MP:0005041
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053874img abnormal immune system physiology MP:0001790
Genes (59)

Species:
human : 59
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCLEC9A283420C-type lectin domain family 9, member A
INFERRED
HumanTIRAP114609toll-interleukin 1 receptor (TIR) domain containing adaptor protein
INFERRED
HumanFCAMR83953Fc receptor, IgA, IgM, high affinity
INFERRED
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
INFERRED
HumanPDCD1LG280380programmed cell death 1 ligand 2
INFERRED
HumanSEMA4A64218sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
INFERRED
HumanBATF355509basic leucine zipper transcription factor, ATF-like 3
INFERRED
HumanMARCH155016membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
INFERRED
HumanERAP151752endoplasmic reticulum aminopeptidase 1
Click here to display 24 evidence detail records.
HumanMAP4K111184mitogen-activated protein kinase kinase kinase kinase 1
INFERRED
HumanMAP3K149020mitogen-activated protein kinase kinase kinase 14
INFERRED
HumanSKAP28935src kinase associated phosphoprotein 2
INFERRED
HumanWAS7454Wiskott-Aldrich syndrome
INFERRED
HumanTNFSF47292tumor necrosis factor (ligand) superfamily, member 4
INFERRED
HumanTPP27174tripeptidyl peptidase II
Click here to display 24 evidence detail records.
HumanTLR47099toll-like receptor 4
INFERRED
HumanTAPBP6892TAP binding protein (tapasin)
INFERRED
HumanTAP16890transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Click here to display 24 evidence detail records.
HumanSYK6850spleen tyrosine kinase
INFERRED
HumanSTAT66778signal transducer and activator of transcription 6, interleukin-4 induced
INFERRED
HumanSTAT26773signal transducer and activator of transcription 2, 113kDa
INFERRED
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
INFERRED
HumanRFX55993regulatory factor X, 5 (influences HLA class II expression)
INFERRED
HumanRELB5971v-rel avian reticuloendotheliosis viral oncogene homolog B
Click here to display 24 evidence detail records.
HumanRAG15896recombination activating gene 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0001835abnormal antigen presentation0self