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Details
Link-It Detail - Jax Mouse Phenotype - abnormal iron level
Debug Stats
  • ### Total Build Time: 231 ms 25.187 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 366 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 419 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 1.015 KB
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 4.173 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.921 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=226 ms Completed: 226 ms rowSize= 15.010 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal iron level MP:0001770
Definition (1)
any anomaly in the concentrations of the metallic element that normally occurs in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins and is an essential component of enzymes such as catalase, peroxidase, and various cytochromes
Parents (2)
img abnormal mineral level MP:0000192
img abnormal iron homeostasis MP:0005637
Children (9)
img abnormal circulating iron level MP:0004152
img abnormal kidney iron level MP:0008742
img hemochromatosis MP:0005638
img abnormal intestinal iron level MP:0008740
img abnormal heart iron level MP:0008741
img abnormal brain iron level MP:0008811
img hemosiderosis MP:0005639
img abnormal spleen iron level MP:0008739
img abnormal liver iron level MP:0008738
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053766img abnormal mineral level MP:0000192
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053766img abnormal iron homeostasis MP:0005637
Genes (74)

Species:
human : 74
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanTMPRSS6164656transmembrane protease, serine 6
Click here to display 35 evidence detail records.
HumanHFE2148738hemochromatosis type 2 (juvenile)
Click here to display 35 evidence detail records.
HumanSPIC121599Spi-C transcription factor (Spi-1/PU.1 related)
INFERRED
HumanBTBD9114781BTB (POZ) domain containing 9
INFERRED
HumanCYBRD179901cytochrome b reductase 1
INFERRED
HumanTTC7A57217tetratricopeptide repeat domain 7A
Click here to display 35 evidence detail records.
HumanANKH56172ANKH inorganic pyrophosphate transport regulator
INFERRED
HumanSLC39A455630solute carrier family 39 (zinc transporter), member 4
INFERRED
HumanSTEAP355240STEAP family member 3, metalloreductase
INFERRED
HumanEXOC654536exocyst complex component 6
INFERRED
HumanSLC40A130061solute carrier family 40 (iron-regulated transporter), member 1
INFERRED
HumanSLC39A229986solute carrier family 39 (zinc transporter), member 2
INFERRED
HumanFBXL526234F-box and leucine-rich repeat protein 5
Click here to display 35 evidence detail records.
HumanABCB811194ATP-binding cassette, sub-family B (MDR/TAP), member 8
INFERRED
HumanHEPH9843hephaestin
Click here to display 35 evidence detail records.
HumanHYAL28692hyaluronoglucosaminidase 2
INFERRED
HumanPICALM8301phosphatidylinositol binding clathrin assembly protein
INFERRED
HumanUROS7390uroporphyrinogen III synthase
INFERRED
HumanTK17083thymidine kinase 1, soluble
INFERRED
HumanTFRC7037transferrin receptor (p90, CD71)
Click here to display 35 evidence detail records.
HumanTFR27036transferrin receptor 2
INFERRED
HumanTF7018transferrin
INFERRED
HumanPRDX27001peroxiredoxin 2
INFERRED
HumanSTAT5B6777signal transducer and activator of transcription 5B
INFERRED
HumanSTAT5A6776signal transducer and activator of transcription 5A
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0001770abnormal iron level0self