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Details
Link-It Detail - Jax Mouse Phenotype - abnormal apical ectodermal ridge morphology
Debug Stats
  • ### Total Build Time: 169 ms 25.010 KB
  • CONCEPT_NAME gt=10 ms Completed: 10 ms rowSize= 414 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 305 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 170 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 1.024 KB
  • CONCEPT_CHILDREN gt=10 ms Completed: 10 ms rowSize= 1.483 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=11 ms Completed: 11 ms rowSize= 4.257 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=114 ms Completed: 114 ms rowSize= 16.052 KB
  • CONCEPT_XREFS gt=8 ms Completed: 8 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal apical ectodermal ridge morphology MP:0001676
Definition (1)
any structural anomaly of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme
Synonyms (1)
"abnormal AER" EXACT
Parents (2)
img abnormal ectoderm development MP:0001675
img abnormal limb bud morphology MP:0005650
Children (3)
img absent apical ectodermal ridge MP:0001677
img thin apical ectodermal ridge MP:0001679
img thick apical ectodermal ridge MP:0001678
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img embryogenesis phenotype MP:00053807img abnormal ectoderm development MP:0001675
img mammalian phenotype MP:0000001img embryogenesis phenotype MP:00053806img abnormal limb bud morphology MP:0005650
img mammalian phenotype MP:0000001img limbs/digits/tail phenotype MP:00053716img abnormal limb bud morphology MP:0005650
Genes (29)

Species:
human : 29
Page Size
Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanRSPO2340419R-spondin 2
Click here to display 39 evidence detail records.
HumanSP8221833Sp8 transcription factor
Click here to display 39 evidence detail records.
HumanFUZ80199fuzzy planar cell polarity protein
Click here to display 39 evidence detail records.
HumanWLS79971wntless homolog (Drosophila)
Click here to display 39 evidence detail records.
HumanLEF151176lymphoid enhancer-binding factor 1
INFERRED
HumanGREM126585gremlin 1, DAN family BMP antagonist
Click here to display 39 evidence detail records.
HumanGPR16123432G protein-coupled receptor 161
INFERRED
HumanDKK122943dickkopf WNT signaling pathway inhibitor 1
INFERRED
HumanHAND29464heart and neural crest derivatives expressed 2
Click here to display 39 evidence detail records.
HumanTP638626tumor protein p63
Click here to display 39 evidence detail records.
HumanTBX36926T-box 3
INFERRED
HumanTBX56910T-box 5
INFERRED
HumanFBXW46468F-box and WD repeat domain containing 4
Click here to display 39 evidence detail records.
HumanRFNG5986RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Click here to display 39 evidence detail records.
HumanPRRX15396paired related homeobox 1
Click here to display 39 evidence detail records.
HumanMYCN4613v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
Click here to display 39 evidence detail records.
HumanMSX14487msh homeobox 1
Click here to display 39 evidence detail records.
HumanLRP64040low density lipoprotein receptor-related protein 6
Click here to display 39 evidence detail records.
HumanLRP44038low density lipoprotein receptor-related protein 4
Click here to display 39 evidence detail records.
HumanJAG23714jagged 2
INFERRED
HumanITGA33675integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Click here to display 39 evidence detail records.
HumanGLI32737GLI family zinc finger 3
INFERRED
HumanGAS12619growth arrest-specific 1
INFERRED
HumanFGFR22263fibroblast growth factor receptor 2
Click here to display 39 evidence detail records.
HumanEN12019engrailed homeobox 1
Click here to display 39 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0001676abnormal apical ectodermal ridge morphology0self