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Details
Link-It Detail - Jax Mouse Phenotype - abnormal optic nerve morphology
Debug Stats
  • ### Total Build Time: 138 ms 28.099 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 390 bytes
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  • CONCEPT_GENES gt=129 ms Completed: 129 ms rowSize= 16.306 KB
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Jax Mouse Phenotype (1)
abnormal optic nerve morphology MP:0001330
Definition (1)
any structural anomaly of the second cranial nerve which is responsible for conveying visual information from the retina to the brain; it extends from the retina to the optic chiasma where part of its fibers become the optic tract and cross to the opposite side and pass to the geniculate bodies
Synonyms (1)
"optic nerve abnormalities" BROAD
Parents (2)
img abnormal posterior eye segment morphology MP:0005195
img abnormal cranial nerve morphology MP:0001056
Children (12)
img optic nerve hypoplasia MP:0006221
img optic nerve compression MP:0006220
img absent optic nerve MP:0001333
img abnormal optic disc morphology MP:0008259
img optic nerve degeneration MP:0006219
img optic nerve swelling MP:0006223
img optic neuropathy MP:0006222
img optic nerve cupping MP:0005497
img enlarged optic nerve MP:0008529
img optic nerve atrophy MP:0001059
img abnormal optic nerve innervation MP:0001332
img abnormal optic chiasm morphology MP:0009770
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img vision/eye phenotype MP:00053915img abnormal posterior eye segment morphology MP:0005195
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036316img abnormal cranial nerve morphology MP:0001056
Genes (81)

Species:
human : 81
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPRSS56646960protease, serine, 56
INFERRED
HumanCISD2493856CDGSH iron sulfur domain 2
Click here to display 74 evidence detail records.
HumanBARHL2343472BarH-like homeobox 2
Click here to display 74 evidence detail records.
HumanVSX2338917visual system homeobox 2
Click here to display 74 evidence detail records.
HumanATOH7220202atonal homolog 7 (Drosophila)
Click here to display 74 evidence detail records.
HumanMTERFD2130916MTERF domain containing 2
INFERRED
HumanNAV289797neuron navigator 2
Click here to display 74 evidence detail records.
HumanNKX6-284504
Click here to display 74 evidence detail records.
HumanSLX484464SLX4 structure-specific endonuclease subunit
INFERRED
HumanOPA380207optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
Click here to display 74 evidence detail records.
HumanFA2H79152fatty acid 2-hydroxylase
Click here to display 74 evidence detail records.
HumanFKRP79147fukutin related protein
INFERRED
HumanSMOC164093SPARC related modular calcium binding 1
INFERRED
HumanNEUROD458158neuronal differentiation 4
Click here to display 74 evidence detail records.
HumanSPTBN457731spectrin, beta, non-erythrocytic 4
Click here to display 74 evidence detail records.
HumanSCYL157410SCY1-like 1 (S. cerevisiae)
Click here to display 74 evidence detail records.
HumanMCOLN157192mucolipin 1
Click here to display 74 evidence detail records.
HumanGJC257165gap junction protein, gamma 2, 47kDa
INFERRED
HumanPOMGNT155624protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
Click here to display 74 evidence detail records.
HumanATP8A251761ATPase, aminophospholipid transporter, class I, type 8A, member 2
INFERRED
HumanTFB1M51106transcription factor B1, mitochondrial
INFERRED
HumanRAX30062retina and anterior neural fold homeobox
Click here to display 74 evidence detail records.
HumanSLC17A526503solute carrier family 17 (acidic sugar transporter), member 5
Click here to display 74 evidence detail records.
HumanVAX225806ventral anterior homeobox 2
INFERRED
HumanSCRIB23513scribbled planar cell polarity protein
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0001330abnormal optic nerve morphology0self