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Details
Link-It Detail - Jax Mouse Phenotype - abnormal keratinocyte apoptosis
Debug Stats
  • ### Total Build Time: 25 ms 29.214 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 390 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 359 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 1.018 KB
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.033 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 2.898 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 22.220 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.169 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal keratinocyte apoptosis MP:0001224
Definition (1)
aberrant programmed cell death or anomaly in the number of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum
Parents (2)
img abnormal apoptosis MP:0001648
img abnormal keratinocyte physiology MP:0003453
Children (2)
img decreased keratinocyte apoptosis MP:0009581
img increased keratinocyte apoptosis MP:0009580
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053846img abnormal apoptosis MP:0001648
img mammalian phenotype MP:0000001img integument phenotype MP:00107715img abnormal keratinocyte physiology MP:0003453
Genes (16)

Species:
human : 16
SpeciesGeneGeneIdGene NameEvidence
HumanMOB1B92597MOB kinase activator 1B
INFERRED
HumanPERP64065PERP, TP53 apoptosis effector
INFERRED
HumanTREX211219three prime repair exonuclease 2
INFERRED
HumanPKP311187plakophilin 3
INFERRED
HumanMAP3K69064mitogen-activated protein kinase kinase kinase 6
INFERRED
HumanIKBKG8517inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INFERRED
HumanTYR7299tyrosinase
img Jax MP, Pubmed Id: 17118961, MOUSE PHENOTYPE ID: MGI:96688
img Jax MP, Pubmed Id: 10751363, MOUSE PHENOTYPE ID: MGI:1891500
img Jax MP, Pubmed Id: 10940923, MOUSE PHENOTYPE ID: MGI:103289
img Jax MP, Pubmed Id: 16988713, MOUSE PHENOTYPE ID: MGI:98880
img Jax MP, Pubmed Id: 16988713, MOUSE PHENOTYPE ID: MGI:99456
HumanKLF107071Kruppel-like factor 10
INFERRED
HumanRELB5971v-rel avian reticuloendotheliosis viral oncogene homolog B
img Jax MP, Pubmed Id: 10940923, MOUSE PHENOTYPE ID: MGI:103289
img Jax MP, Pubmed Id: 16988713, MOUSE PHENOTYPE ID: MGI:99456
img Jax MP, Pubmed Id: 16988713, MOUSE PHENOTYPE ID: MGI:98880
img Jax MP, Pubmed Id: 10751363, MOUSE PHENOTYPE ID: MGI:1891500
img Jax MP, Pubmed Id: 17118961, MOUSE PHENOTYPE ID: MGI:96688
HumanMAP2K15604mitogen-activated protein kinase kinase 1
INFERRED
HumanPPARD5467peroxisome proliferator-activated receptor delta
INFERRED
HumanMC1R4157melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
img Jax MP, Pubmed Id: 16988713, MOUSE PHENOTYPE ID: MGI:99456
img Jax MP, Pubmed Id: 10940923, MOUSE PHENOTYPE ID: MGI:103289
img Jax MP, Pubmed Id: 17118961, MOUSE PHENOTYPE ID: MGI:96688
img Jax MP, Pubmed Id: 10751363, MOUSE PHENOTYPE ID: MGI:1891500
img Jax MP, Pubmed Id: 16988713, MOUSE PHENOTYPE ID: MGI:98880
HumanKRT143861keratin 14
img Jax MP, Pubmed Id: 10940923, MOUSE PHENOTYPE ID: MGI:103289
img Jax MP, Pubmed Id: 16988713, MOUSE PHENOTYPE ID: MGI:98880
img Jax MP, Pubmed Id: 10751363, MOUSE PHENOTYPE ID: MGI:1891500
img Jax MP, Pubmed Id: 16988713, MOUSE PHENOTYPE ID: MGI:99456
img Jax MP, Pubmed Id: 17118961, MOUSE PHENOTYPE ID: MGI:96688
HumanESR22100estrogen receptor 2 (ER beta)
INFERRED
HumanCEBPB1051CCAAT/enhancer binding protein (C/EBP), beta
INFERRED
HumanCASP3836caspase 3, apoptosis-related cysteine peptidase
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0001224abnormal keratinocyte apoptosis0self