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Details
Link-It Detail - Jax Mouse Phenotype - abnormal microglial cell morphology
Debug Stats
  • ### Total Build Time: 495 ms 29.921 KB
  • CONCEPT_NAME gt=202 ms Completed: 202 ms rowSize= 398 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 496 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1.031 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.480 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 9.651 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=282 ms Completed: 282 ms rowSize= 15.567 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.173 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal microglial cell morphology MP:0000136
Definition (1)
any structural anomaly of the small, migratory, phagocytic, interstitial cells derived from myeloid progenitor cells and found in the parenchyma of the central nervous system; microglia are scavengers, engulfing dead cells and other debris, and in Alzheimer's disease, microglia are found associated with dying nerve cells and amyloid plaques
Parents (2)
img abnormal macrophage morphology MP:0002446
img abnormal CNS glial cell morphology MP:0000952
Children (3)
img decreased microglial cell number MP:0011982
img microgliosis MP:0008918
img abnormal microglial cell differentiation MP:0011981
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:00053979img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539710img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img immune system phenotype MP:000538710img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img hematopoietic system phenotype MP:000539711img abnormal macrophage morphology MP:0002446
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036316img abnormal CNS glial cell morphology MP:0000952
Genes (60)

Species:
human : 60
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanSUMF1285362sulfatase modifying factor 1
Click here to display 56 evidence detail records.
HumanIL34146433interleukin 34
Click here to display 56 evidence detail records.
HumanLRRK2120892leucine-rich repeat kinase 2
INFERRED
HumanNXNL1115861nucleoredoxin-like 1
INFERRED
HumanMPP564398membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
INFERRED
HumanSCYL157410SCY1-like 1 (S. cerevisiae)
INFERRED
HumanGJC257165gap junction protein, gamma 2, 47kDa
INFERRED
HumanTRIB228951tribbles homolog 2 (Drosophila)
INFERRED
HumanABHD1226090abhydrolase domain containing 12
INFERRED
HumanARSG22901arylsulfatase G
Click here to display 56 evidence detail records.
HumanAFG3L210939AFG3 ATPase family member 3-like 2 (S. cerevisiae)
INFERRED
HumanPSTPIP29050proline-serine-threonine phosphatase interacting protein 2
Click here to display 56 evidence detail records.
HumanTYROBP7305TYRO protein tyrosine kinase binding protein
Click here to display 56 evidence detail records.
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
Click here to display 56 evidence detail records.
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
Click here to display 56 evidence detail records.
HumanSPP16696secreted phosphoprotein 1
Click here to display 56 evidence detail records.
HumanRHO6010rhodopsin
INFERRED
HumanPEX55830peroxisomal biogenesis factor 5
INFERRED
HumanPTPN65777protein tyrosine phosphatase, non-receptor type 6
Click here to display 56 evidence detail records.
HumanPSMC45704proteasome (prosome, macropain) 26S subunit, ATPase, 4
INFERRED
HumanPSEN15663presenilin 1
Click here to display 56 evidence detail records.
HumanPLP15354proteolipid protein 1
Click here to display 56 evidence detail records.
HumanPITX35309paired-like homeodomain 3
INFERRED
HumanOGG149688-oxoguanine DNA glycosylase
INFERRED
HumanNPC14864Niemann-Pick disease, type C1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0000136abnormal microglial cell morphology0self