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GATACA
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Details
Link-It Detail - Pathway - Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
Debug Stats
  • ### Total Build Time: 25 ms 16.310 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 252 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_DEFINITION gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=21 ms Completed: 21 ms rowSize= 14.781 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.108 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Pathway (1)
Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. sa_g1_and_s_phases
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanNXT129107NTF2-like export factor 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1423828
HumanTP537157tumor protein p53
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0079419
HumanPRB15542proline-rich protein BstNI subfamily 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1418866
HumanMDM24193MDM2 oncogene, E3 ubiquitin protein ligase
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0812222
HumanE2F21870E2F transcription factor 2
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1414223
HumanE2F11869E2F transcription factor 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0812258
HumanCFL11072cofilin 1 (non-muscle)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1413355
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0525037
HumanCDKN1B1027cyclin-dependent kinase inhibitor 1B (p27, Kip1)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332737
HumanCDKN1A1026cyclin-dependent kinase inhibitor 1A (p21, Cip1)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0249197
HumanCDK41019cyclin-dependent kinase 4
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C0694873
HumanCDK21017cyclin-dependent kinase 2
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332733
HumanCCND1595cyclin D1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1413172
HumanARF3377ADP-ribosylation factor 3
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1412506
HumanARF1375ADP-ribosylation factor 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1412504
XRefs (1)

XRef Types:
pathway : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
PATHWAYimg sa_g1_and_s_phasesCdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.0self