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Details
Link-It Detail - Pathway - Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
Debug Stats
  • ### Total Build Time: 28 ms 16.629 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 255 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_DEFINITION gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=23 ms Completed: 23 ms rowSize= 15.095 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.111 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Pathway (1)
Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. sa_caspase_cascade
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanSCAP22937SREBF chaperone
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1822619
HumanSREBF26721sterol regulatory element binding transcription factor 2
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1420399
HumanSREBF16720sterol regulatory element binding transcription factor 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1420398
HumanPRF15551perforin 1 (pore forming protein)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1418887
HumanGZMB3002granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1415380
HumanDFFB1677DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1413983
HumanDFFA1676DNA fragmentation factor, 45kDa, alpha polypeptide
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1413982
HumanCASP10843caspase 10, apoptosis-related cysteine peptidase
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332661
HumanCASP9842caspase 9, apoptosis-related cysteine peptidase
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332668
HumanCASP8841caspase 8, apoptosis-related cysteine peptidase
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332667
HumanCASP7840caspase 7, apoptosis-related cysteine peptidase
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332666
HumanCASP3836caspase 3, apoptosis-related cysteine peptidase
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1413132
HumanBIRC3330baculoviral IAP repeat containing 3
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332415
HumanBIRC2329baculoviral IAP repeat containing 2
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332414
HumanAPAF1317apoptotic peptidase activating factor 1
img MSigDB: C2.cp - SigmaAldrich, UMLKSK CUI: C1332098
XRefs (1)

XRef Types:
pathway : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
PATHWAYimg sa_caspase_cascadeApoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.0self