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Details
Link-It Detail - Pathway - Genes involved in EGFR downregulation
Debug Stats
  • ### Total Build Time: 29 ms 25.037 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 214 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_DEFINITION gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=26 ms Completed: 26 ms rowSize= 23.573 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.081 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Pathway (1)
Genes involved in EGFR downregulation reactome_egfr_downregulation
Genes (24)

Species:
human : 24
SpeciesGeneGeneIdGene NameEvidence
HumanEPS15L158513epidermal growth factor receptor pathway substrate 15-like 1
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1428396
HumanSH3KBP130011SH3-domain kinase binding protein 1
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1422243
HumanEPN129924epsin 1
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1427640
HumanSTAM210254signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1420452
HumanSPRY210253sprouty homolog 2 (Drosophila)
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1420383
HumanSPRY110252sprouty homolog 1, antagonist of FGF signaling (Drosophila)
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1420382
HumanHGS9146hepatocyte growth factor-regulated tyrosine kinase substrate
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1366514
HumanARHGEF78874Rho guanine nucleotide exchange factor (GEF) 7
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1423613
HumanSTAM8027signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1420451
HumanUBB7314ubiquitin B
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1421262
HumanSH3GL26456SH3-domain GRB2-like 2
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1420026
HumanGRB22885growth factor receptor-bound protein 2
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1333707
HumanEPS152060epidermal growth factor receptor pathway substrate 15
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1333343
HumanEGFR1956epidermal growth factor receptor
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1414313
HumanEGF1950epidermal growth factor
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1367721
HumanCLTC1213clathrin, heavy chain (Hc)
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1413512
HumanCLTA1211clathrin, light chain A
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1413510
HumanAP2S11175adaptor-related protein complex 2, sigma 1 subunit
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1412445
HumanAP2M11173adaptor-related protein complex 2, mu 1 subunit
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1412444
HumanCDC42998cell division cycle 42
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1366537
HumanCBL867Cbl proto-oncogene, E3 ubiquitin protein ligase
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C0812242
HumanAP2B1163adaptor-related protein complex 2, beta 1 subunit
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1412443
HumanAP2A2161adaptor-related protein complex 2, alpha 2 subunit
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1412442
HumanAP2A1160adaptor-related protein complex 2, alpha 1 subunit
img MSigDB: C2.cp - Reactome, UMLKSK CUI: C1412441
XRefs (1)

XRef Types:
pathway : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
PATHWAYimg reactome_egfr_downregulationGenes involved in EGFR downregulation0self