Human | NPS | 594857 | neuropeptide S | NPS acts as a novel modulator of arousal and anxiety-related behaviours by promoting a unique pattern of effects: stimulation associated with anxiolysis |
Human | ANKK1 | 255239 | ankyrin repeat and kinase domain containing 1 | for men, but not for women, we observed a strong and specific association between low neuroticism-anxiety and the A1+ allele of the DRD2 TaqI A polymorphism |
Human | TPH2 | 121278 | tryptophan hydroxylase 2 | A significant association between harm avoidance (HA), a trait related to anxiety, and tryptophan hydroxylase 2 polymorphism |
Human | DTNBP1 | 84062 | dystrobrevin binding protein 1 | DTNBP1 haplotypes, which have been found to be risk factors for schizophrenia, are unlikely to be risk factors for anxiety and depression |
Human | PINK1 | 65018 | PTEN induced putative kinase 1 | |
Human | JPH3 | 57338 | junctophilin 3 | |
Human | GAL | 51083 | galanin/GMAP prepropeptide | The involvement of galanin is reviewed in the modulation of such functions as neurotransmitter release, memory, pain, depression, anxiety, obesity, gut motility, neuroendocrine regulation, development and neuroregeneration |
Human | PDE11A | 50940 | phosphodiesterase 11A | |
Human | VPS13A | 23230 | vacuolar protein sorting 13 homolog A (S. cerevisiae) | |
Human | SGCE | 8910 | sarcoglycan, epsilon | Severe myoclonus-dystonia syndrome characterized by obsessive-compulsive disorder, depression, and anxiety was shown to be associated with a novel truncating mutation located within exon 4 of SGCE |
Human | ALDH5A1 | 7915 | aldehyde dehydrogenase 5 family, member A1 | |
Human | TPH1 | 7166 | tryptophan hydroxylase 1 | Title:Tryptophan hydroxylase gene 218A/C polymorphism is associated with somatic anxiety in major depressive disorder.|Association:Y|Conclusion:The polymorphism in serotonergic system related genes may be associated with depressive symptoms in major depressive disorder. The results suggest that analysis of clusters that narrow down the phenotype may be more suitable in genetic studies of major depressive illness. |
Human | NKX2-1 | 7080 | | Movements are exacerbated by anxiety |
Human | SNCA | 6622 | synuclein, alpha (non A4 component of amyloid precursor) | These results indicate a possible role for alpha-synuclein in anxiety-like behaviours |
Human | SLC6A4 | 6532 | solute carrier family 6 (neurotransmitter transporter), member 4 | Click here to display 20 evidence detail records. |
Human | SDHD | 6392 | succinate dehydrogenase complex, subunit D, integral membrane protein | Anxiety (with pheochromocytoma) |
Human | SDHC | 6391 | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | Anxiety (with pheochromocytoma) |
Human | SDHB | 6390 | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | Anxiety (with pheochromocytoma) |
Human | RGS2 | 5997 | regulator of G-protein signaling 2, 24kDa | variations of the Rgs2 gene play a role also for the development of anxiety in humans |
Human | PRNP | 5621 | prion protein | |
Human | PRKAR1A | 5573 | protein kinase, cAMP-dependent, regulatory, type I, alpha | |
Human | PPP2R2B | 5521 | protein phosphatase 2, regulatory subunit B, beta | |
Human | OXT | 5020 | oxytocin/neurophysin I prepropeptide | Depressed women had more variability in pulsatile oxytocin release during 2 test tasks, & higher oxytocin levels during the 1-hour affiliation-focused imagery session which were also associated with more depression, anxiety, & interpersonal dysfunction |
Human | OPRM1 | 4988 | opioid receptor, mu 1 | Lack of association of a single-nucleotide polymorphism of the mu-opioid receptor gene with anxiety-related traits |
Human | NPY | 4852 | neuropeptide Y | haplotype-driven NPY expression predicts brain responses to emotional and stress challenges and also inversely correlates with trait anxiety |