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Details
Link-It Detail - Disease - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Debug Stats
  • ### Total Build Time: 235 ms 40.919 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 386 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 582 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 4.146 KB
  • CONCEPT_RELATIONSHIPS gt=187 ms Completed: 187 ms rowSize= 16.595 KB
  • CONCEPT_GENES gt=22 ms Completed: 22 ms rowSize= 17.449 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.182 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma C1961099
Definition (1)
A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Precursor Cell Lymphoblastic Leukemia-Lymphoma C1961102
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Precursor Cell Lymphoblastic Leukemia-Lymphoma C1961102
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210706img Precursor Cell Lymphoblastic Leukemia-Lymphoma C1961102
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242286img Precursor Cell Lymphoblastic Leukemia-Lymphoma C1961102
Relationships (99)

Relation Types:
diso_​to_​anat : 23
diso_​to_​chem : 24
diso_​to_​diso : 40
diso_​to_​gene : 6
diso_​to_​phen : 1
diso_​to_​phys : 5


Relationships:
none : 34
gene_​associated_​with_​disease : 6
gene_​product_​malfunction_​associated_​with_​disease : 2
is_​abnormal_​cell_​of_​disease : 9
is_​normal_​cell_​origin_​of_​disease : 5
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 3
isa : 5
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​cytogenetic_​abnormality_​of_​disease : 14
may_​be_​finding_​of_​disease : 7
may_​be_​molecular_​abnormality_​of_​disease : 3
permuted_​term_​of : 1
used_​for : 2
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN236img genetic aspects C0017399
DISO_to_CHEM52img NOTCH 001 RECEPTOR C0144507
DISO_to_CHEM52img Receptor, Notch1 C0144507
DISO_to_PHYS40img Mutation C0026882
DISO_to_DISO31img Precursor B-Cell Lymphoblastic Leukemia-Lymphoma C0023485
DISO_to_DISO29img Complication Aspects C1171258
DISO_to_PHYS28img Signal Transduction C0037083
DISO_to_CHEM23img Antineoplastic Agents C0003392
DISO_to_PHYS23img GENE EXPRESSION REG LEUKEMIC C0017267
DISO_to_DISO17img Chromosomal translocation C0040715
DISO_to_PHYS17img Apoptosis C0162638
DISO_to_CHEM16img NEOPL PROTEINS C0027642
DISO_to_CHEM16img Neoplasm Proteins C0027642
DISO_to_ANAT15img T-Lymphocyte C0039194
DISO_to_CHEM15img Cellular Proto Oncogene Proteins C0033712
DISO_to_CHEM14img Cell Cycle Protein C0243021
DISO_to_CHEM14img Cell Cycle Proteins C0243021
DISO_to_CHEM14img Homeo Domain Proteins C0242617
DISO_to_CHEM14img Homeodomain Proteins C0242617
DISO_to_DISO14img Leukemia, Myelocytic, Acute C0023467
DISO_to_CHEM13img Chimeric Oncogene Proteins C0029014
DISO_to_CHEM13img TRANSCRIPTION FACTOR C0040648
DISO_to_PHYS13img Gene Expression Regulation, Neoplastic C0017268
DISO_to_CHEM12img F-Box Proteins C1257945
DISO_to_CHEM12img Notch Proteins C0083792
Genes (12)

Species:
human : 12
SpeciesGeneGeneIdGene NameEvidence
HumanTLX330012T-cell leukemia homeobox 3
img GENERIF, Score=1000, Pubmed Id: 17308084, UMLKSK CUI: C1961099
img GENERIF, Score=1000, Pubmed Id: 12970786, UMLKSK CUI: C1961099
img GENERIF, Score=1000, Pubmed Id: 15990867, UMLKSK CUI: C1961099
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
img GENERIF, Score=1000, Pubmed Id: 17495957, UMLKSK CUI: C1961099
HumanTP537157tumor protein p53
img GAD, Score=1000, Pubmed Id: 8180387, UMLKSK CUI: C1961099
HumanTAL16886T-cell acute lymphocytic leukemia 1
img GENERIF, Score=1000, Pubmed Id: 18439091, UMLKSK CUI: C1961099
HumanNOTCH14851notch 1
img GENERIF, Score=991, Pubmed Id: 16298817, UMLKSK CUI: C1961099
img GENERIF, Score=991, Pubmed Id: 18184405, UMLKSK CUI: C1961099
img GENERIF, Score=947, Pubmed Id: 16880534, UMLKSK CUI: C1961099
img GENERIF, Score=1000, Pubmed Id: 16079893, UMLKSK CUI: C1961099
img GENERIF, Score=991, Pubmed Id: 15472075, UMLKSK CUI: C1961099
HumanMYB4602v-myb avian myeloblastosis viral oncogene homolog
img GENERIF, Score=947, Pubmed Id: 17435759, UMLKSK CUI: C1961099
HumanIL83576interleukin 8
img GENERIF, Score=1000, Pubmed Id: 18322253, UMLKSK CUI: C1961099
HumanTLX13195T-cell leukemia homeobox 1
img GENERIF, Score=991, Pubmed Id: 17609427, UMLKSK CUI: C1961099
HumanFLT32322fms-related tyrosine kinase 3
img GENERIF, Score=939, Pubmed Id: 16326981, UMLKSK CUI: C1961099
HumanCD34947CD34 molecule
img GENERIF, Score=947, Pubmed Id: 18683236, UMLKSK CUI: C1961099
HumanCCND3896cyclin D3
img GENERIF, Score=901, Pubmed Id: 17300668, UMLKSK CUI: C1961099
HumanBMI1648BMI1 polycomb ring finger oncogene
img GENERIF, Score=947, Pubmed Id: 17989714, UMLKSK CUI: C1961099
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1961099Precursor T-Cell Lymphoblastic Leukemia-Lymphoma0self