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Details
Link-It Detail - Disease - Prostatic Hyperplasia
Debug Stats
  • ### Total Build Time: 68 ms 21.579 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 340 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 403 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=9 ms Completed: 9 ms rowSize= 554 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 1.512 KB
  • CONCEPT_RELATIONSHIPS gt=5 ms Completed: 5 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=22 ms Completed: 22 ms rowSize= 17.323 KB
  • CONCEPT_XREFS gt=14 ms Completed: 14 ms rowSize= 1.155 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Prostatic Hyperplasia C1739363
Definition (1)
Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
Semantic Types (1)
Pathologic Function (T046)
Parents (1)
img Prostatic Diseases C0033575
Ancestral Roots
RootRoot Plus OneDepthParent
img Male Urogenital Diseases C1720894img Genital Diseases, Male C00174124img Prostatic Diseases C0033575
Genes (10)

Species:
human : 10
SpeciesGeneGeneIdGene NameEvidence
HumanAKR1C38644aldo-keto reductase family 1, member C3
img GAD, Score=1000, Pubmed Id: 16302261, UMLKSK CUI: C1739363
HumanSRD5A26716steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
img GAD, Score=1000, Pubmed Id: 12370109, UMLKSK CUI: C1739363
img GAD, Score=1000, Pubmed Id: 15136785, UMLKSK CUI: C1739363
img GAD, Score=1000, Pubmed Id: 15389785, UMLKSK CUI: C1739363
HumanSRD5A16715steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
img GAD, Score=1000, Pubmed Id: 15136785, UMLKSK CUI: C1739363
HumanHSD3B13283hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
img GAD, Score=1000, Pubmed Id: 16302261, UMLKSK CUI: C1739363
HumanCYP19A11588cytochrome P450, family 19, subfamily A, polypeptide 1
img GAD, Score=1000, Pubmed Id: 16302261, UMLKSK CUI: C1739363
HumanCYP17A11586cytochrome P450, family 17, subfamily A, polypeptide 1
img GAD, Score=1000, Pubmed Id: 12370109, UMLKSK CUI: C1739363
HumanCYP3A41576cytochrome P450, family 3, subfamily A, polypeptide 4
img GAD, Score=1000, Pubmed Id: 12644831, UMLKSK CUI: C1739363
HumanAR367androgen receptor
img GAD, Score=1000, Pubmed Id: 15136785, UMLKSK CUI: C1739363
img GAD, Score=1000, Pubmed Id: 12370109, UMLKSK CUI: C1739363
HumanKLK3354kallikrein-related peptidase 3
img GAD, Score=1000, Pubmed Id: 16302261, UMLKSK CUI: C1739363
HumanADRA1A148adrenoceptor alpha 1A
img GAD, Score=1000, Pubmed Id: 15136785, UMLKSK CUI: C1739363
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C1739363Prostatic Hyperplasia0self